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. 2023 May;130(5):217-220.
doi: 10.5177/ntvt.2023.05.22089.

[What is known about the diagnosis and treatment of herpes labialis?]

[Article in Dutch]

[What is known about the diagnosis and treatment of herpes labialis?]

[Article in Dutch]
M V Starink. Ned Tijdschr Tandheelkd. 2023 May.

Abstract

Herpes labialis is one of the most common skin infections. In most people it is asymptomatic or mildly symptomatic, but very severe cases do occur. Herpes remains latent and can recur. Herpes labialis is a clinical diagnosis. If in doubt, additional testing can be carried out, usually polymerase chain reaction. There are no treatments that can eliminate the virus. In case of more severe symptoms and frequent recurrences, there may be an indication for treatment. In case of mild complaints, topical zinc sulphate/zinc oxide and analgesics (systemic or topical lidocaine) will suffice. More severe complaints and frequent recurrences can be treated with antiviral creams (Aciclovir) or with systemic antiviral medication (Valaciclovir). In frequent recurrences, prophylactic Valaciclovir can also be given for a period of many months. Treatment should be started as soon as possible and will slightly shorten the duration of the disease.

Herpes labialis is een van de meest voorkomende huidinfecties. Bij de meeste mensen verloopt het asymptomatisch of zijn er milde symptomen, maar er kan ook sprake zijn van heftige aanvallen. Herpes blijft latent aanwezig en kan recidiveren. De diagnose herpes labialis wordt klinisch vastgesteld. Bij twijfel kan aanvullend onderzoek worden verricht, meestal polymerasekettingreactie. Er zijn geen behandelingen die het virus kunnen elimineren. Bij heftiger symptomen en frequente recidieven kan er wel een behandelindicatie zijn. Bij milde klachten kan worden volstaan met topisch zinksulfaat/zinkoxide en analgetica (systemische of topische lidocaïne). Bij ernstiger klachten en frequente recidieven kan behandeld worden met antivirale crèmes (aciclovir) of met systemische antivirale medicatie (valaciclovir). Bij frequente recidieven kan ook profylactisch valaciclovir gedurende vele maanden worden gegeven. Behandeling moet zo snel mogelijk worden gestart; deze verkort de ziekteduur in geringe mate.

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