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Editorial
. 2023 Jul 4;49(4):829-830.
doi: 10.1093/schbul/sbad061.

Improving our Understanding of Early Psychosis: Learning from the Optimise Trial

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Editorial

Improving our Understanding of Early Psychosis: Learning from the Optimise Trial

Belinda Lennox. Schizophr Bull. .
No abstract available

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References

    1. Susai SR, F Föcking M, Mongan D, Heurich M, Coutts F, et al. . Association of complement and coagulation pathway proteins with treatment response in first-episode psychosis: a longitudinal analysis of the OPTiMiSE. Schizophr Bull. 2023:sbac201. - PMC - PubMed
    1. Gorelik A, Sapir T, Haffner-Krausz R, Olender T, Woodruff TM, Reiner O.. Developmental activities of the complement pathway in migrating neurons. Nat Commun. 2017;8:15096. - PMC - PubMed
    1. Yilmaz M, Yalcin E, Presumey Jet al. . Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice. Nat Neurosci. 2021; 24(2):214–224. - PMC - PubMed
    1. Sekar A, Bialas A, de Rivera H, et al. . Schizophrenia risk from complex variation of complement component 4. Nature. 2016;530:177–183. - PMC - PubMed
    1. Laskaris L, Chana G, Weickert CS, et al. . Increased C3 and C4 proteins in serum of FEP and UHR patients: implications for inflammatory subtyping in SCZ. Biol Psychiatry. 2017;81:S27–S28.