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Comment
. 2023 May 8;58(9):725-726.
doi: 10.1016/j.devcel.2023.04.008.

Improving stem cell-derived pancreatic islets using single-cell multi-inferred regulomes

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Improving stem cell-derived pancreatic islets using single-cell multi-inferred regulomes

Maria F Rubin de Celis et al. Dev Cell. .
Free article

Abstract

In this issue of Developmental Cell, Zhu et al. provide integrated data from single-cell/nuclei RNAseq and chromatin accessibility (ATAC) across both a multistaged differentiation protocol-deriving pancreatic islets from hESCs and primary islets. This important resource could be leveraged for optimizing the differentiation and maturation of pancreatic islet cells from hESCs.

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Conflict of interest statement

Declaration of interests The authors declare they have no conflict of interest.

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