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[Preprint]. 2023 Apr 24:rs.3.rs-2837899.
doi: 10.21203/rs.3.rs-2837899/v1.

Association of receiving opioid medication-assisted treatment with sexual identity and mental health/substance use disorder symptoms in a nationally representative sample of adults

David Adzrago  1 , Gabrielle S Evans  1 , Emanuelle M Dias  1 , Victoria Kwentua  1 , Grace Elizabeth White  1 , J Michael Wilkerson  1
Affiliations

Association of receiving opioid medication-assisted treatment with sexual identity and mental health/substance use disorder symptoms in a nationally representative sample of adults

David Adzrago et al. Res Sq. .

Abstract

Background: Although the literature suggests that medication-assisted treatment (MAT) is an effective treatment for opioid use disorder, limited studies have assessed the prevalence or the association between MAT use and sexual identity, mental health, or substance use disorder among a nationally representative sample. We assessed the prevalence and association of opioid MAT use between sexual identity, depressive disorder symptoms, alcohol use dependence, and marijuana use dependence in the United States.

Methods: We used the 2019 National Survey on Drug Use and Health public-use data on adults aged 18-64 years (N = 38,841) to conduct a weighted multivariable logistic regression analysis.

Results: A total of 4.80% and 2.32% of the population identified as bisexual and lesbian/gay, respectively. About 0.31% (612,750 people) of the population reported receiving opioid MAT, 3.73% had alcohol use dependence, 1.42% had marijuana use dependence, and 9.13% had major depressive episode (MDE) symptoms. Of those who had received opioid MAT, 0.57% were bisexuals and 1.07% were lesbians/gays, 0.65% were people with alcohol use dependence, 2.32% with marijuana use dependence, and 1.59% with MDE symptoms. Lesbian/gay individuals were more likely to receive opioid MAT (AOR = 3.43, 95% CI = 1.42, 8.25) compared to heterosexual individuals. The odds were higher for people with marijuana use dependence (AOR = 3.44, 95% CI = 1.47, 8.06) and MDE symptoms (AOR = 5.22, 95% CI = 3.46, 7.89) than their counterparts.

Conclusions: In this study, sexual minorities, people with MDE symptoms, and those dependent on marijuana use were more likely to receive opioid MAT, suggesting the need to investigate further opioid use disorder symptoms and their risk factors among these populations.

Keywords: Depression; Opioid medication-assisted treatment; Opioid use; Sexual minority; substance use disorder.

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Conflict of interest statement

Competing interests The authors have no competing interests to declare that are relevant to the content of this article.

References

    1. Substance Abuse and Mental Health Services Administration (2021) Key substance use and mental health indicators in the United States: Results from the 2020 National Survey on Drug Use and Health (HHS Publication No. PEP21–07-01–003, NSDUH Series H-56). Rockville, MD: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration. https://www.samhsa.gov/data/
    1. Centers for Disease Control and Prevention (2021)Opioid basics. https://www.cdc.gov/opioids/basics/index.html
    1. National Institute on Drug Abuse (2021) Opioids. https://www.drugabuse.gov/drug-topics/opioids
    1. Bosetti C, Santucci C, Radrezza S, Erthal J, Berterame S, Corli O (2019) Trends in the consumption of opioids for the treatment of severe pain in Europe, 1990–2016. Eur J Pain 23(4):697–707. - PubMed
    1. Zöllner C, Stein C (2006) Opioids. Analgesia 31–63.

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