In reply: Sex-specific outcomes in COVID-19: missing pieces of the puzzle

Georg Wolff¹, Bernhard Wernly², Hans Flaatten³, Jesper Fjølner⁴, Raphael Romano Bruno¹, Antonio Artigas⁵, Bernardo Bollen Pinto⁶, Joerg C Schefold⁷, Malte Kelm¹, Stephan Binneboessel¹, Philipp Baldia¹, Michael Beil⁸, Sigal Sivri⁸, Peter Vernon van Heerden⁹, Wojciech Szczeklik¹⁰, Muhammed Elhadi¹¹, Michael Joannidis¹², Sandra Oeyen¹³, Maria Flamm¹⁴, Brian Marsh¹⁵, Finn H Andersen^{16

17}, Rui Moreno¹⁸, Ariane Boumendil^{19

20}, Dylan W De Lange²¹, Bertrand Guidet^{19

20}, Susannah Leaver²², Christian Jung²³; COVIP study group

Affiliations

¹ Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
² Department of Anaesthesiology, Perioperative Medicine and Intensive Care Medicine, Paracelsus Medical University, Salzburg, Austria.
³ Department of Clinical Medicine, Department of Anaesthesia and Intensive Care, Haukeland University Hospital, University of Bergen, Bergen, Norway.
⁴ Department of Intensive Care, Aarhus University Hospital, Aarhus, Denmark.
⁵ Department of Intensive Care Medicine, CIBER Enfermedades Respiratorias, Corporacion Sanitaria Universitaria Parc Tauli, Autonomous University of Barcelona, Sabadell, Spain.
⁶ Department of Acute Medicine, Geneva University Hospitals, Geneva, Switzerland.
⁷ Department of Intensive Care Medicine, Inselspital, Universitätsspital, University of Bern, Bern, Switzerland.
⁸ Department of Medical Intensive Care, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
⁹ Department of Anesthesia, Intensive Care and Pain Medicine, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
¹⁰ Department of Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland.
¹¹ Faculty of Medicine, University of Tripoli, Tripoli, Libya.
¹² Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University Innsbruck, Innsbruck, Austria.
¹³ Department of Intensive Care 1K12IC, Ghent University Hospital, Ghent, Belgium.
¹⁴ Institute of General Practice, Family Medicine and Preventive Medicine, Paracelsus Medical University, Salzburg, Austria.
¹⁵ Mater Misericordiae University Hospital, Dublin, Ireland.
¹⁶ Department of Anesthesia and Intensive Care, Ålesund Hospital, Ålesund, Norway.
¹⁷ Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
¹⁸ Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Faculdade de Ciências Médicas de Lisboa, Nova Médical School, Unidade de Cuidados Intensivos Neurocríticos e Trauma, Lisbon, Portugal.
¹⁹ UPMC Univ Paris, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Equipe: épidémiologie hospitalière qualité et organisation des soins, Sorbonne Universités, Paris, France.
²⁰ Assistance Publique - Hôpitaux de Paris, service de réanimation médicale, Hôpital Saint-Antoine, Paris, France.
²¹ Department of Intensive Care Medicine, University Medical Center, University Utrecht, Utrecht, The Netherlands.
²² General Intensive Care, St George´s University Hospitals NHS Foundation Trust, London, UK.
²³ Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany. christian.jung@med.uni-duesseldorf.de.

PMID: 37165131
PMCID: PMC10171910
DOI: 10.1007/s12630-023-02470-x

Comment

In reply: Sex-specific outcomes in COVID-19: missing pieces of the puzzle

Georg Wolff et al. Can J Anaesth. 2023 Jun.

. 2023 Jun;70(6):1110-1112.

doi: 10.1007/s12630-023-02470-x. Epub 2023 May 10.

Authors

Affiliations

¹ Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
² Department of Anaesthesiology, Perioperative Medicine and Intensive Care Medicine, Paracelsus Medical University, Salzburg, Austria.
³ Department of Clinical Medicine, Department of Anaesthesia and Intensive Care, Haukeland University Hospital, University of Bergen, Bergen, Norway.
⁴ Department of Intensive Care, Aarhus University Hospital, Aarhus, Denmark.
⁵ Department of Intensive Care Medicine, CIBER Enfermedades Respiratorias, Corporacion Sanitaria Universitaria Parc Tauli, Autonomous University of Barcelona, Sabadell, Spain.
⁶ Department of Acute Medicine, Geneva University Hospitals, Geneva, Switzerland.
⁷ Department of Intensive Care Medicine, Inselspital, Universitätsspital, University of Bern, Bern, Switzerland.
⁸ Department of Medical Intensive Care, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
⁹ Department of Anesthesia, Intensive Care and Pain Medicine, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
¹⁰ Department of Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland.
¹¹ Faculty of Medicine, University of Tripoli, Tripoli, Libya.
¹² Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University Innsbruck, Innsbruck, Austria.
¹³ Department of Intensive Care 1K12IC, Ghent University Hospital, Ghent, Belgium.
¹⁴ Institute of General Practice, Family Medicine and Preventive Medicine, Paracelsus Medical University, Salzburg, Austria.
¹⁵ Mater Misericordiae University Hospital, Dublin, Ireland.
¹⁶ Department of Anesthesia and Intensive Care, Ålesund Hospital, Ålesund, Norway.
¹⁷ Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
¹⁸ Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Faculdade de Ciências Médicas de Lisboa, Nova Médical School, Unidade de Cuidados Intensivos Neurocríticos e Trauma, Lisbon, Portugal.
¹⁹ UPMC Univ Paris, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Equipe: épidémiologie hospitalière qualité et organisation des soins, Sorbonne Universités, Paris, France.
²⁰ Assistance Publique - Hôpitaux de Paris, service de réanimation médicale, Hôpital Saint-Antoine, Paris, France.
²¹ Department of Intensive Care Medicine, University Medical Center, University Utrecht, Utrecht, The Netherlands.
²² General Intensive Care, St George´s University Hospitals NHS Foundation Trust, London, UK.
²³ Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany. christian.jung@med.uni-duesseldorf.de.

PMID: 37165131
PMCID: PMC10171910
DOI: 10.1007/s12630-023-02470-x

No abstract available

Keywords: COVID-19; SARS-CoV-2; sex-specific outcomes; thrombotic complications.

PubMed Disclaimer

Conflict of interest statement

The authors state that there is nothing to disclose in addition to disclosures in the original article.

Comment on

Sex-specific outcomes in COVID-19: missing pieces of the puzzle.
Magoon R, Choudhary N. Magoon R, et al. Can J Anaesth. 2023 Jun;70(6):1108-1109. doi: 10.1007/s12630-023-02469-4. Epub 2023 May 10. Can J Anaesth. 2023. PMID: 37165130 Free PMC article. No abstract available.

References

1. Magoon R, Choudhary N. Sex-specific outcomes in COVID-19: missing pieces of the puzzle. Can J Anesth. 2023 doi: 10.1007/s12630-023-02469-4. - DOI - PMC - PubMed
1. Wolff G, Wernly B, Flaatten H, et al. Sex-specific treatment characteristics and 30-day mortality outcomes of critically ill COVID-19 patients over 70 years of age-results from the prospective COVIP study. Can J Anesth. 2022;69:1390–1398. doi: 10.1007/s12630-022-02304-2. - DOI - PMC - PubMed
1. Jung C, Flaatten H, Fjølner J, et al. The impact of frailty on survival in elderly intensive care patients with COVID-19: the COVIP study. Crit Care. 2021;25:149. doi: 10.1186/s13054-021-03551-3. - DOI - PMC - PubMed
1. Wilcox T, Smilowitz NR, Seda B, Xia Y, Hochman J, Berger JS. Sex differences in thrombosis and mortality in patients hospitalized for COVID-19. Am J Cardiol. 2022;170:112–117. doi: 10.1016/j.amjcard.2022.01.024. - DOI - PMC - PubMed
1. REMAP-CAP Investigators, ACTIV-4a Investigators, ATTACC Investigators, et al. Therapeutic anticoagulation with heparin in critically ill patients with Covid-19. N Engl J Med 2021; 385: 777–89. 10.1056/nejmoa2103417 - PMC - PubMed

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In reply: Sex-specific outcomes in COVID-19: missing pieces of the puzzle

Affiliations

In reply: Sex-specific outcomes in COVID-19: missing pieces of the puzzle

Authors

Affiliations

Conflict of interest statement

Comment on

References

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LinkOut - more resources

Full Text Sources

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