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Multicenter Study
. 2023 May 12;23(1):250.
doi: 10.1186/s12872-023-03273-0.

Reply to the letter "Understanding lactate and its clearance during extracorporeal membrane oxygenation for supporting refractory cardiogenic shock patients"

Affiliations
Multicenter Study

Reply to the letter "Understanding lactate and its clearance during extracorporeal membrane oxygenation for supporting refractory cardiogenic shock patients"

Fernando Luís Scolari et al. BMC Cardiovasc Disord. .

Abstract

This is a reply to the letter titled "Understanding lactate and its clearance during extracorporeal membrane oxygenation for supporting refractory cardiogenic shock patients" by Eva Rully Kurniawati et al. In response to the concerns raised about our paper published in BMC Cardiovascular Disorders, titled "Association between serum lactate levels and mortality in patients with cardiogenic shock receiving mechanical circulatory support: a multicenter retrospective cohort study," we have addressed the confounding bias on the population included and the use of VA-ECMO and Impella CP. Furthermore, we have provided new data on the correlation of oxygen supply and lactate levels at admission of cardiogenic shock.

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Conflict of interest statement

All authors have no competing interests.

Figures

Fig. 1
Fig. 1
Linear correlation of the lactate level with pO2 at the admission of cardiogenic shock patients

References

    1. van Diepen S, Katz JN, Albert NM, Henry TD, Jacobs AK, Kapur NK, et al. Contemporary Management of Cardiogenic Shock: A Scientific Statement from the American Heart Association. Circulation. 2017;136:e232–68. - PubMed
    1. Tehrani BN, Truesdell AG, Psotka MA, Rosner C, Singh R, Sinha SS, et al. A standardized and comprehensive approach to the management of cardiogenic shock. JACC: Heart Failure. 2020;8:879–91. - PMC - PubMed
    1. Scolari FL, Schneider D, Fogazzi DV, Gus M, Rover MM, Bonatto MG et al. Association between serum lactate levels and mortality in patients with cardiogenic shock receiving mechanical circulatory support: a multicenter retrospective cohort study. BMC Cardiovasc Disord. 2020;20. - PMC - PubMed
    1. Yeh YC, Lee CT, Wang CH, Tu YK, Lai CH, Wang YC, et al. Investigation of microcirculation in patients with venoarterial extracorporeal membrane oxygenation life support. Crit Care. 2018;22:1–9. doi: 10.1186/s13054-018-2081-2. - DOI - PMC - PubMed
    1. Scolari FL, Abelson S, Brahmbhatt DH, Medeiros JJF, Fan CPS, Fung NL, et al. Clonal haematopoiesis is associated with higher mortality in patients with cardiogenic shock. Eur J Heart Fail. 2022;24:1573–82. doi: 10.1002/ejhf.2588. - DOI - PubMed

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