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. 2023 Apr 23;13(9):1520.
doi: 10.3390/diagnostics13091520.

Use of the Dialkylcarbamoylchloride Dressing in the Care of Central Venous Access Exit Site in a Pediatric and Neonatal Population

Giorgio Lamberti  1 , Vincenzo Domenichelli  1 , Simona Straziuso  1 , Gabriella Pelusi  1 , Miria Natile  2 , Gina Ancora  2 , Giovanni Barone  2
Affiliations

Use of the Dialkylcarbamoylchloride Dressing in the Care of Central Venous Access Exit Site in a Pediatric and Neonatal Population

Giorgio Lamberti et al. Diagnostics (Basel). .

Abstract

Dialkylcarbamoylchloride dressing is a fatty acid derivative that has been shown in vitro to bind a number of pathogenic microorganisms. The purpose of this prospective study was to evaluate the safety and the efficacy of this technology in the care of the exit site of central venous catheter in a paediatric and neonatal population.

Methods: The study was conducted from September 2020 to December 2022 at the Infermi Hospital in Rimini. Central venous catheters were placed using the SIC bundle for insertion. Dialkylcarbamoylchloride dressing was placed below the subcutaneous anchoring at the time of CVC placement and at each dressing change. Data about the catheters and the exit site were recorded and then compared with an historical cohort.

Results: 118 catheters were placed during the studied period. The dialkylcarbamoylchloride dressing was well-tolerated. No case of systemic or local infection was recorded. The comparison with the historical cohort showed a reduction in the rate of exit site infection (p value 0.03).

Conclusion: Dialkylcarbamoylchloride dressing is well-tolerated in paediatric and neonatal population. It represents a promising tool as a strategy for infection prevention.

Keywords: central venous catheter; dialkylcarbamoylchloride; dressing; exit site; exit site infection.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
DACC dressing.
Figure 2
Figure 2
Centrally inserted central catheter in a paediatric patient stabilized with Securacath. DACC dressing is placed below the Securacath.
See this image and copyright information in PMC

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