Molecular and Cellular Mechanisms of Corneal Scarring and Advances in Therapy

Matthias Fuest^{1

2}, Vishal Jhanji³, Gary Hin-Fai Yam^{3

4

5}

Affiliations

¹ Department of Ophthalmology, RWTH Aachen University, 52074 Aachen, Germany.
² Cornea Bank Aachen, RWTH Aachen University, 52074 Aachen, Germany.
³ Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA 15213, USA.
⁴ Singapore Eye Research Institute, Singapore 169856, Singapore.
⁵ McGowan Institute for Regenerative Medicine, Pittsburgh, PA 15213, USA.

Editorial

Matthias Fuest et al. Int J Mol Sci. 2023.

. 2023 Apr 24;24(9):7777.

doi: 10.3390/ijms24097777.

Matthias Fuest^{1

2}, Vishal Jhanji³, Gary Hin-Fai Yam^{3

4

5}

¹ Department of Ophthalmology, RWTH Aachen University, 52074 Aachen, Germany.
² Cornea Bank Aachen, RWTH Aachen University, 52074 Aachen, Germany.
³ Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA 15213, USA.
⁴ Singapore Eye Research Institute, Singapore 169856, Singapore.
⁵ McGowan Institute for Regenerative Medicine, Pittsburgh, PA 15213, USA.

Abstract

On the basis of WHO global blindness data, it may be stated that 23 million people globally suffer from unilateral corneal blindness, while 4 [...].

The authors declare no conflict of interest.

1. Pascolini D., Mariotti S.P. Global estimates of visual impairment: 2010. Br. J. Ophthalmol. 2012;96:614–618. doi: 10.1136/bjophthalmol-2011-300539. - DOI - PubMed
1. Gain P., Jullienne R., He Z., Aldossary N., Acquart S., Cognasse F., Thuret G. Global survey of corneal transplantation and eye banking. JAMA Ophthalmol. 2016;134:167–173. doi: 10.1001/jamaophthalmol.2015.4776. - DOI - PubMed
1. Claesson M., Armitage W.J. Ten-year follow-up of graft survival and visual outcome after penetrating keratoplasty in Sweden. Cornea. 2009;28:1124–1129. doi: 10.1097/ICO.0b013e3181a2a7a6. - DOI - PubMed
1. Vats D.P., Parihar J., Rodrigues F., Ramchandran N., Dash R.G., Trehan H.S., Khan M.A. Penetrating keratoplasty in high risk cases. Med. J. Armed Forces India. 2001;57:16–18. doi: 10.1016/S0377-1237(01)80082-4. - DOI - PMC - PubMed
1. Arranz-Marquez E., Katsanosm A., Kozoobolis V.P., Konstas A.G., Teus M.A. A critical overview of the biological effects of Mitomycin C application on the cornea following refractive surgery. Adv. Ther. 2019;36:786–797. doi: 10.1007/s12325-019-00905-w. - DOI - PMC - PubMed