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Clinical Trial
. 2023 Oct;37(10):e1211-e1214.
doi: 10.1111/jdv.19195. Epub 2023 Jun 12.

Lack of effect of benralizumab on signs and symptoms of moderate-to-severe atopic dermatitis: Results from the phase 2 randomized, double-blind, placebo-controlled HILLIER trial

E Guttman-Yassky  1 , L Bahadori  2 , L Brooks  3 , K L Clark  3 , H Grindebacke  4 , C N Ho  5 , R Katial  6   7 , T-H Pham  8 , C Walton  3 , C J Datto  2 ; HILLIER study group†
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Clinical Trial

Lack of effect of benralizumab on signs and symptoms of moderate-to-severe atopic dermatitis: Results from the phase 2 randomized, double-blind, placebo-controlled HILLIER trial

E Guttman-Yassky et al. J Eur Acad Dermatol Venereol. 2023 Oct.
No abstract available

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References

REFERENCES

    1. Jenerowicz D, Czarnecka-Operacz M, Silny W. Peripheral blood eosinophilia in atopic dermatitis. ACTA Derm Alp Pannonica Adriat. 2007;16(2):47-52.
    1. Chiesa Fuxench ZC, Block JK, Boguniewicz M, Boyle J, Fonacier L, Gelfand JM, et al. Atopic dermatitis in America study: a cross-sectional study examining the prevalence and disease burden of atopic dermatitis in the US adult population. J Invest Dermatol. 2019;139(3):583-90. https://doi.org/10.1016/j.jid.2018.08.028
    1. Bieber T, Simpsom EL, Thaci D, et al. Abrocitinib versus placebo or dupilumab for atopic dermatitis. N Engl J Med. 2021;384(12):1101-12. https://doi.org/10.1056/NEJMoa2019380
    1. Silverberg JI, Gelfand JM, Margolis DJ, Boguniewicz M, Fonacier L, Grayson MH, et al. Pain is a common and burdensome symptom of atopic dermatitis in United States adults. J Allergy Clin Immunol. 2018;7(8):2699-2706.e7. https://doi.org/10.1016/j.jaip.2019.05.055
    1. Rasheed Z, Zedan K, Saif GB, Salama RH, Salem T, Ahmed AA, et al. Markers of atopic dermatitis, allergic rhinitis and bronchial asthma in pediatric patients: correlation with Filaggrin, eosinophil major basic protein and immunoglobulin E. Clin Mol Allergy. 2018;16(23):1-9. https://doi.org/10.1186/s12948-018-0102-y

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