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Case Reports
. 2023 Jan-Mar;38(1):50-52.
doi: 10.4103/ijnm.ijnm_85_22. Epub 2023 Feb 24.

18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scan Findings in a Rare Case of Subcutaneous Panniculitis-Like T-Cell Lymphoma

Affiliations
Case Reports

18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scan Findings in a Rare Case of Subcutaneous Panniculitis-Like T-Cell Lymphoma

Madan Gopal Vishnoi et al. Indian J Nucl Med. 2023 Jan-Mar.

Abstract

Skin lymphomas are less common and subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a fairly rare subtype of primary cutaneous lymphoma. Skin lymphomas involve subcutaneous adipose tissues with no involvement of lymph nodes. Diagnosis of these cases is generally a challenge to clinicians. These cases present with fever, weight loss, and local discomfort in the region of involvement of subcutaneous tissues and sometime with skin eczema and rashes. Positron emission tomography/computed tomography (PET/CT) scan can guide in determining the extent of involvement being whole-body imaging and can guide the site of biopsy and can help to prevent misdiagnosis. It also helps in correct and early diagnosis and successful treatment. We report a case of a young adult who presented with pyrexia of unknown origin in which PET/CT scan revealed mildly fluorodeoxyglucose-avid diffuse subcutaneous panniculitis involving the whole body, trunk, and extremities. Biopsy was taken from the most appropriate site according to the PET/CT scan report and reported as SPTCL.

Keywords: 18F-fluorodeoxyglucose positron emission tomography/computed tomography; pyrexia of unknown origin; subcutaneous panniculitis.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
MIP, sagittal, coronal, and axial images of the thorax region show diffuse subcutaneous panniculitis involving the whole body both trunk and extremities. MIP: Maximum intensity projection
Figure 2
Figure 2
MIP, sagittal, coronal, and axial images of the thorax region show metabolic resolution of diffuse subcutaneous panniculitis (posttreatment) involving the whole body. MIP: Maximum intensity projection

References

    1. Gonzalez CL, Medeiros LJ, Braziel RM, Jaffe ES. T-cell lymphoma involving subcutaneous tissue. A clinicopathologic entity commonly associated with hemophagocytic syndrome. Am J Surg Pathol. 1991;15:17–27. - PubMed
    1. Willemze R, Cerroni L, Kempf W, Berti E, Facchetti F, Swerdlow SH, et al. The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas. Blood. 2019;133:1703–14. - PMC - PubMed
    1. Porcia T, Bradford, Susan S, Devesa, William F, Adenson, Jorge R, Toro Incidence patterns in the United States: A population based study of 3884 cases by. Blood. 2009;13:5064–73. - PMC - PubMed
    1. Hoque SR, Child FJ, Whittaker SJ, Ferreira S, Orchard G, Jenner K, et al. Subcutaneous panniculitis-like T-cell lymphoma: A clinicopathological, immunophenotypic and molecular analysis of six patients. Br J Dermatol. 2003;148:516–25. - PubMed
    1. Levine BD, Seeger LL, James AW, Motamedi K. Subcutaneous panniculitis-like T-cell lymphoma: MRI features and literature review. Skeletal Radiol. 2014;43:1307–11. - PubMed

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