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Case Reports
. 2023 Apr 10;15(4):e37407.
doi: 10.7759/cureus.37407. eCollection 2023 Apr.

A Case Report of Brucellosis-Associated Infective Endocarditis

Affiliations
Case Reports

A Case Report of Brucellosis-Associated Infective Endocarditis

Syed Muhammad Hussain Zaidi et al. Cureus. .

Abstract

Brucellosis is a prevalent zoonotic infection that can be relatively well managed and tolerated if appropriate treatment is initiated. Unfortunately, likely secondary to decreased awareness and vague symptoms, the diagnosis can be easily missed leading to worsening complications that severely increase the mortality rate. We present a case of a 25-year-old female who presented from a rural setting with a diagnosis of brucellosis, which was delayed. She ultimately developed infective endocarditis with cardiac vegetations on imaging. Despite improvement on antibiotics and reduction in size of cardiac vegetation, she suffered a fatal cardiac arrest before undergoing surgical intervention. Better awareness regarding hygiene and sanitary food handling should be encouraged, especially in underdeveloped rural areas, to help prevent infection. More studies need to be performed to help better identify symptoms coupled with maintaining a high index of suspicion so as to expedite diagnosis, treatment, management and hopefully prevent the progression of disease and worsening complications.

Keywords: brucellosis; endocarditis; unpasteurized dairy products; valvular vegetation; veterinarians.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Cardiomegaly and a calcified foci in the left upper zone

References

    1. The new global map of human brucellosis. Pappas G, Papadimitriou P, Akritidis N, Christou L, Tsianos EV. Lancet Infect Dis. 2006;6:91–99. - PubMed
    1. Brucellosis as an emerging threat in developing economies: lessons from Nigeria. Ducrotoy MJ, Bertu WJ, Ocholi RA, Gusi AM, Bryssinckx W, Welburn S, Moriyón I. PLoS Negl Trop Dis. 2014;8:0. - PMC - PubMed
    1. Epidemiological modeling of bovine brucellosis in India. Kang GJ, Gunaseelan L, Abbas KM. Proc IEEE Int Conf Big Data. 2014;2014:6–10. - PMC - PubMed
    1. Brucella endocarditis - a series of five case reports. Raju IT, Solanki R, Patnaik AN, Barik RC, Kumari NR, Gulati AS. Indian Heart J. 2013;65:72–77. - PMC - PubMed
    1. ELISA is superior to bacterial culture and agglutination test in the diagnosis of brucellosis in an endemic area in China. Xu N, Wang W, Chen F, Li W, Wang G. BMC Infect Dis. 2020;20:11. - PMC - PubMed

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