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Editorial
. 2023 Jul;223(1):280-281.
doi: 10.1192/bjp.2023.51.

The emergence of primary negative symptoms: relevance of timing?

Eric Yu Hai Chen  1   2 , Stephanie Ming Yin Wong  1 , Christy Lai Ming Hui  1 , Yi Nam Suen  1 , Sherry Kit Wa Chan  1   2
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Editorial

The emergence of primary negative symptoms: relevance of timing?

Eric Yu Hai Chen et al. Br J Psychiatry. 2023 Jul.

Abstract

Negative symptoms are an important symptom dimension in schizophrenia that are often least responsive to antipsychotic medications. We revisit the current practice of identifying 'primary' negative symptoms and suggest that its concept would benefit from a further elaboration of their timing of emergence in relation to the dynamic neurobiological changes to enhance their utility in clinical decision-making and research.

Keywords: Negative symptoms; clinical decisions; primary negative symptoms; psychopathology.

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