Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Meta-Analysis
. 2023 Oct 1;19(10):1835-1843.
doi: 10.5664/jcsm.10622.

Sleep duration is associated with metabolic syndrome in adolescents and children: a systematic review and meta-analysis

Yiyang Xu  1   2 , Jianian Hua  1   3 , Jiahe Wang  4 , Yueping Shen  1
Affiliations
Meta-Analysis

Sleep duration is associated with metabolic syndrome in adolescents and children: a systematic review and meta-analysis

Yiyang Xu et al. J Clin Sleep Med. .

Abstract

Study objectives: Studies on the associations between sleep duration and metabolic syndrome in adolescents and children have reported mixed results. To shed more light on this issue, we conducted this meta-analysis by synthesizing the results of previous studies.

Methods: Studies were retrieved from PubMed, Ovid, Cochrane, and Embase from inception to October 2021. Fixed-effects models and random-effects models were used to analyze the effects of sleep time on metabolic syndrome in adolescents.

Results: Data from 7 studies, including 13,305 adolescents and children, were meta-analyzed. Compared with the control group, short sleep durations were not associated with a high prevalence of metabolic syndrome in adolescents and children using a random-effects model (odds ratio = 0.92, 95% confidence interval = 0.48-1.37, I2 = 56.5%, P = .378). Using a fixed-effects model on long sleep duration, this association was statistically significant (odds ratio = 0.57, 95% confidence interval = 0.38-0.76, I2 = 0.0%, P < .001) as a protective factor compared with shorter sleep duration.

Conclusions: Long sleep duration, instead of short sleep duration, was significantly associated with a lower prevalence of metabolic syndrome among adolescents and children.

Citation: Xu Y, Hua J, Wang J, Shen Y. Sleep duration is associated with metabolic syndrome in adolescents and children: a systematic review and meta-analysis. J Clin Sleep Med. 2023;19(10):1835-1843.

Keywords: adolescents; meta-analysis; metabolic syndrome; sleep duration.

PubMed Disclaimer

Conflict of interest statement

All authors were involved in writing the paper and have seen and approved the manuscript. This study was funded by the National Natural Science Foundation of China (Project No. 81973143). The authors report no conflicts of interest.

Figures

Figure 1
Figure 1. Workflow of the search process.
MetS = metabolic syndrome.
Figure 2
Figure 2. Association between long sleep duration and the prevalence of metabolic syndrome using a fixed-effects model.
CI = confidence interval, OR = odds ratio.
Figure 3
Figure 3. Association between short sleep duration and the prevalence of metabolic syndrome using a random-effects model.
CI = confidence interval, OR = odds ratio.
See this image and copyright information in PMC

References

    1. National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) . Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report . Circulation. 2002. ; 106 ( 25 ): 3143 – 3421 . - PubMed
    1. de Ferranti SD , Gauvreau K , Ludwig DS , Neufeld EJ , Newburger JW , Rifai N . Prevalence of the metabolic syndrome in American adolescents: findings from the third National Health and Nutrition Examination Survey . Circulation. 2004. ; 110 ( 16 ): 2494 – 2497 . - PubMed
    1. Cook S , Weitzman M , Auinger P , Nguyen M , Dietz WH . Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third National Health and Nutrition Examination Survey, 1988-1994 . Arch Pediatr Adolesc Med. 2003. ; 157 ( 8 ): 821 – 827 . - PubMed
    1. Pirkola J , Tammelin T , Bloigu A , et al. . Prevalence of metabolic syndrome at age 16 using the International Diabetes Federation paediatric definition . Arch Dis Child. 2008. ; 93 ( 11 ): 945 – 951 . - PubMed
    1. Mbowe O , Diaz A , Wallace J , Mazariegos M , Jolly P . Prevalence of metabolic syndrome and associated cardiovascular risk factors in Guatemalan school children . Matern Child Health J. 2014. ; 18 ( 7 ): 1619 – 1627 . - PMC - PubMed

Publication types