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Observational Study
. 2023 Apr;7(1):e001865.
doi: 10.1136/bmjpo-2023-001865.

Critical disease related to SARS-CoV-2 infection in children from the Amazon region: an observational study

Emmerson Carlos Franco de Farias  1 , Manoel Jaime Castro Pavão Júnior  2 , Susan C D de Sales  2 , Luciana M P P do Nascimento  2 , Mary de Mello  3 , Patricia Carvalho  4 , Maria Teresa Terreri  5 , Gleice Clemente  5
Affiliations
Observational Study

Critical disease related to SARS-CoV-2 infection in children from the Amazon region: an observational study

Emmerson Carlos Franco de Farias et al. BMJ Paediatr Open. 2023 Apr.

Abstract

This is a multicentre prospective cohort including critically ill children and adolescents, with confirmed critical disease related to SARS-CoV-2, admitted to three tertiary paediatric intensive care units in the Brazilian Amazon, between April 2020 and July 2022. 208 patients were included (median age was 3.5 years). The majority had malnutrition (62%) and comorbidities (60.6%). Mechanical ventilation support, cardiogenic shock and acute respiratory distress syndrome occurred in 47%, 30% and 34.1% of patients, respectively. There were 37 (18%) deaths. A poor outcome of severe COVID-19 and multisystem inflammatory syndrome in children was observed in children and adolescents from the Brazilian Amazon.

Keywords: COVID-19; Epidemiology; Virology.

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Conflict of interest statement

Competing interests: None declared.

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Supplementary concepts