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Editorial
. 2023 May 16:12:e88595.
doi: 10.7554/eLife.88595.

A groom with a view

Jeffrey E Markowitz  1
Affiliations
Editorial

A groom with a view

Jeffrey E Markowitz. Elife. .

Abstract

Mapping mouse grooming episodes to neural activity shows that striatal cells deep in the brain collectively represent key aspects of self-grooming.

Keywords: innate behavior; innate naturalistic behavior; mouse; neuroscience; self-grooming; striatum.

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Conflict of interest statement

JM No competing interests declared

Figures

Figure 1.
Figure 1.. Striatal activity collectively represents key features of mouse grooming.
Mouse grooming episodes (depicted within box) involve certain behaviors such as rubbing the eyes and ears with paws. By simultaneously recording mouse behavior and neural activity in the striatum – a key brain structure known to be involved in sequencing behavior – Minkowicz et al. showed that the activity of striatal cells is orchestrated to represent the important timepoints in a grooming sequence: when grooming starts (green); when grooming stops (purple); at both the start and end of the grooming episode (‘border’, grey) and for the duration of the episode (blue).
See this image and copyright information in PMC

Comment on

References

    1. Aldridge JW, Berridge KC. Coding of serial order by neostriatal neurons: A ‘natural action’ approach to movement sequence. The Journal of Neuroscience. 1998;18:2777–2787. doi: 10.1523/JNEUROSCI.18-07-02777.1998. - DOI - PMC - PubMed
    1. Barbera G, Liang B, Zhang L, Gerfen CR, Culurciello E, Chen R, Li Y, Lin D-T. Spatially compact neural clusters in the dorsal striatum encode locomotion relevant information. Neuron. 2016;92:202–213. doi: 10.1016/j.neuron.2016.08.037. - DOI - PMC - PubMed
    1. Berridge KC, Whishaw IQ. Cortex, striatum and cerebellum: Control of serial order in a grooming sequence. Experimental Brain Research. 1992;90:275–290. doi: 10.1007/BF00227239. - DOI - PubMed
    1. Cromwell HC, Berridge KC. Implementation of action sequences by a neostriatal site: A lesion mapping study of grooming syntax. The Journal of Neuroscience. 1996;16:3444–3458. doi: 10.1523/JNEUROSCI.16-10-03444.1996. - DOI - PMC - PubMed
    1. Dhawale AK, Wolff SBE, Ko R, Ölveczky BP. The basal ganglia control the detailed kinematics of learned motor skills. Nature Neuroscience. 2021;24:1256–1269. doi: 10.1038/s41593-021-00889-3. - DOI - PMC - PubMed

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