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. 2023 May;104(5):001848.
doi: 10.1099/jgv.0.001848.

ICTV Virus Taxonomy Profile: Hypoviridae 2023

Sotaro Chiba  1 , Leonardo Velasco  2 , María A Ayllón  3   4 , Nobuhiro Suzuki  5 , Shin-Yi Lee-Marzano  6 , Lying Sun  7 , Sead Sabanadzovic  8 , Massimo Turina  9
Affiliations

ICTV Virus Taxonomy Profile: Hypoviridae 2023

Sotaro Chiba et al. J Gen Virol. 2023 May.

Abstract

Hypoviridae is a family of capsidless viruses with positive-sense RNA genomes of 7.3-18.3 kb that possess either a single large open reading frame (ORF) or two ORFs. The ORFs appear to be translated from genomic RNA by non-canonical mechanisms, i.e. internal ribosome entry site- and stop/restart translation. This family includes the genera Alphahypovirus, Betahypovirus, Gammahypovirus, Deltahypovirus, Epsilonhypovirus, Zetahypovirus, Thetahypovirus and Etahypovirus. Hypovirids have been detected in ascomycetous and basidiomycetous filamentous fungi and are considered to replicate in host, Golgi apparatus-derived, lipid vesicles that contain virus dsRNA as the replicative form. Some hypovirids induce hypovirulence to host fungi, while others do not. This is a summary of the ICTV report on the family Hypoviridae, which is available at www.ictv.global/report/hypoviridae.

Keywords: Hypoviridae; ICTV Report; Taxonomy.

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Conflict of interest statement

The authors declare that there are no conflicts of interest.

Figures

Fig. 1.
Fig. 1.. Genome organization of representative members of the family Hypoviridae. Arrows represent known sites of autoproteolysis. The abbreviations RdRP, Hel and UGT refer to the RNA-directed RNA polymerase, RNA helicase and UDP-glucose/sterol glucosyltransferase domains, respectively. IRES, internal ribosomal entry site; Pro, protease.
See this image and copyright information in PMC

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