STAT6 joins the gain-of-function club

Affiliations

¹ Division of Immunology, Department of Pediatrics, University of Washington and Seattle Children's Research Institute, Seattle, Wash.
² Division of Immunology, Department of Pediatrics, University of Washington and Seattle Children's Research Institute, Seattle, Wash. Electronic address: ealle2@uw.edu.

Editorial

Karin Chen et al. J Allergy Clin Immunol. 2023 Jul.

. 2023 Jul;152(1):53-55.

doi: 10.1016/j.jaci.2023.05.003. Epub 2023 May 14.

¹ Division of Immunology, Department of Pediatrics, University of Washington and Seattle Children's Research Institute, Seattle, Wash.
² Division of Immunology, Department of Pediatrics, University of Washington and Seattle Children's Research Institute, Seattle, Wash. Electronic address: ealle2@uw.edu.

No abstract available

Keywords: Allergic disease; STAT6; gain-of-function; inborn errors of immunity; primary atopic disorders.

Comment on

Severe allergic dysregulation due to a gain of function mutation in the transcription factor STAT6.
Baris S, Benamar M, Chen Q, Catak MC, Martínez-Blanco M, Wang M, Fong J, Massaad MJ, Sefer AP, Kara A, Babayeva R, Eltan SB, Yucelten AD, Bozkurtlar E, Cinel L, Karakoc-Aydiner E, Zheng Y, Wu H, Ozen A, Schmitz-Abe K, Chatila TA. Baris S, et al. J Allergy Clin Immunol. 2023 Jul;152(1):182-194.e7. doi: 10.1016/j.jaci.2023.01.023. Epub 2023 Feb 8. J Allergy Clin Immunol. 2023. PMID: 36758835 Free PMC article.