Neoadjuvant immunotherapy for melanoma is now ready for clinical practice

Claus Garbe^#¹, Reinhard Dummer^#^{2

3}, Teresa Amaral⁴, Rodabe N Amaria⁵, Paolo A Ascierto⁶, Elizabeth M Burton⁵, Brigitte Dreno⁷, Alexander M M Eggermont^{8

9}, Axel Hauschild¹⁰, Christoph Hoeller¹¹, Roland Kaufmann¹², Celeste Lebbe¹³, Mario Mandala¹⁴, Alexander M Menzies^{15

16

17}, David Moreno¹⁸, Olivier Michielin¹⁹, Paul Nathan²⁰, Sapna P Patel⁵, Caroline Robert²¹, Dirk Schadendorf^{22

23}, Paul C Lorigan²⁴, Richard A Scolyer^{15

16

17}, Hussein A Tawbi⁵, Bart A van de Wiel²⁵, Christian Blank^{26

27}, Georgina V Long^{15

16

17}

Affiliations

¹ Centre for Dermatooncology, Department of Dermatology, Eberhard Karls University, Tuebingen, Germany. claus.garbe@med.uni-tuebingen.de.
² Department of Dermatology, University Hospital Zürich (USZ), Zürich, Switzerland. Reinhard.Dummer@usz.ch.
³ Faculty of Medicine, University of Zürich (UZH), Zürich, Switzerland. Reinhard.Dummer@usz.ch.
⁴ Centre for Dermatooncology, Department of Dermatology, Eberhard Karls University, Tuebingen, Germany.
⁵ Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
⁶ Department of Skin Cancer, Cancer Immunotherapy and Development Therapeutics, Instituto Nazionale Tumouri IRCCS Fondazione G. Pascale, Napoli, Italy.
⁷ Nantes University, Nantes, France.
⁸ Faculty of Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
⁹ Comprehensive Cancer Centre Munich of the Technical University Munich and the Ludwig Maximilians University, Munich, Germany.
¹⁰ Department of Dermatology, University Hospital Schleswig-Holstein (UKSH), Kiel, Germany.
¹¹ Department of Dermatology, Medical University of Vienna, Vienna, Austria.
¹² Department of Dermatology, Venerology and Allergology, Frankfurt University Hospital, Frankfurt, Germany.
¹³ Université Paris Cite, AP-HP Department of Dermatology, Hôpital Saint-Louis Paris, Paris, France.
¹⁴ Department of Surgery and Medicine, Unit of Medical Oncology, University of Perugia, Perugia, Italy.
¹⁵ Melanoma Institute Australia, The University of Sydney, Sydney, New South Wales, Australia.
¹⁶ Royal North Shore and Mater Hospitals, Sydney, New South Wales, Australia.
¹⁷ Faculty of Medicine & Health, The University of Sydney, Sydney, NSW, Australia.
¹⁸ Medical & Surgical Dermatology Service, Hospital Universitario Virgen Macarena, Sevilla, Spain.
¹⁹ Department of Medical Oncology, Lausanne University Hospital, Lausanne, Switzerland.
²⁰ Mount Vernon Cancer Centre, Northwood, UK.
²¹ Department of Medical Oncology, Gustave Roussy and Paris-Saclay University, Villejuif, France.
²² Department of Dermatology, University Hospital Essen, Essen, Germany.
²³ German Cancer Consortium, Heidelberg Partner Site Essen, Essen, Germany.
²⁴ University of Manchester, Manchester, UK.
²⁵ Department of Pathology, Netherlands Cancer Institute (NKI), Amsterdam, The Netherlands.
²⁶ Department of Medical Oncology, Netherlands Cancer Institute (NKI), Amsterdam, The Netherlands.
²⁷ Leiden University Medical Centre (LUMC), Leiden, The Netherlands.

^# Contributed equally.

PMID: 37193799
DOI: 10.1038/s41591-023-02336-1

Neoadjuvant immunotherapy for melanoma is now ready for clinical practice

Claus Garbe et al. Nat Med. 2023 Jun.

. 2023 Jun;29(6):1310-1312.

doi: 10.1038/s41591-023-02336-1.

Authors

Affiliations

¹ Centre for Dermatooncology, Department of Dermatology, Eberhard Karls University, Tuebingen, Germany. claus.garbe@med.uni-tuebingen.de.
² Department of Dermatology, University Hospital Zürich (USZ), Zürich, Switzerland. Reinhard.Dummer@usz.ch.
³ Faculty of Medicine, University of Zürich (UZH), Zürich, Switzerland. Reinhard.Dummer@usz.ch.
⁴ Centre for Dermatooncology, Department of Dermatology, Eberhard Karls University, Tuebingen, Germany.
⁵ Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
⁶ Department of Skin Cancer, Cancer Immunotherapy and Development Therapeutics, Instituto Nazionale Tumouri IRCCS Fondazione G. Pascale, Napoli, Italy.
⁷ Nantes University, Nantes, France.
⁸ Faculty of Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
⁹ Comprehensive Cancer Centre Munich of the Technical University Munich and the Ludwig Maximilians University, Munich, Germany.
¹⁰ Department of Dermatology, University Hospital Schleswig-Holstein (UKSH), Kiel, Germany.
¹¹ Department of Dermatology, Medical University of Vienna, Vienna, Austria.
¹² Department of Dermatology, Venerology and Allergology, Frankfurt University Hospital, Frankfurt, Germany.
¹³ Université Paris Cite, AP-HP Department of Dermatology, Hôpital Saint-Louis Paris, Paris, France.
¹⁴ Department of Surgery and Medicine, Unit of Medical Oncology, University of Perugia, Perugia, Italy.
¹⁵ Melanoma Institute Australia, The University of Sydney, Sydney, New South Wales, Australia.
¹⁶ Royal North Shore and Mater Hospitals, Sydney, New South Wales, Australia.
¹⁷ Faculty of Medicine & Health, The University of Sydney, Sydney, NSW, Australia.
¹⁸ Medical & Surgical Dermatology Service, Hospital Universitario Virgen Macarena, Sevilla, Spain.
¹⁹ Department of Medical Oncology, Lausanne University Hospital, Lausanne, Switzerland.
²⁰ Mount Vernon Cancer Centre, Northwood, UK.
²¹ Department of Medical Oncology, Gustave Roussy and Paris-Saclay University, Villejuif, France.
²² Department of Dermatology, University Hospital Essen, Essen, Germany.
²³ German Cancer Consortium, Heidelberg Partner Site Essen, Essen, Germany.
²⁴ University of Manchester, Manchester, UK.
²⁵ Department of Pathology, Netherlands Cancer Institute (NKI), Amsterdam, The Netherlands.
²⁶ Department of Medical Oncology, Netherlands Cancer Institute (NKI), Amsterdam, The Netherlands.
²⁷ Leiden University Medical Centre (LUMC), Leiden, The Netherlands.

^# Contributed equally.

PMID: 37193799
DOI: 10.1038/s41591-023-02336-1

No abstract available

PubMed Disclaimer

References

1. Amaria, R. N. et al. Lancet Oncol. 20, e378–e389 (2019). - DOI - PubMed
1. Topalian, S. L. et al. Science 367, eaax0182 (2020). - DOI - PubMed - PMC
1. Versluis, J. M. et al. Nat. Med. 26, 475–484 (2020). - DOI - PubMed
1. Blank, C. U. et al. Nat. Med. 24, 1655–1661 (2018). - DOI - PubMed
1. Eggermont, A. M. M. et al. NEJM Evidence 1, EVIDoa2200214 (2022). - DOI

MeSH terms

Actions
Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
- Nature Publishing Group
Medical
- MedlinePlus Health Information

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Neoadjuvant immunotherapy for melanoma is now ready for clinical practice

Affiliations

Neoadjuvant immunotherapy for melanoma is now ready for clinical practice

Authors

Affiliations

References

MeSH terms

LinkOut - more resources

Full Text Sources

Medical