Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1979 Jan;24(1):53-64.
doi: 10.1007/BF01297239.

A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents

R E Pemberton, L J Strand
Clinical Trial

A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents

R E Pemberton et al. Dig Dis Sci. 1979 Jan.

Abstract

Newer nonsteroidal antiinflammatory agents (NSAI's) such as ibuprofen, neproxen, fenoprofen, and tolmetin have broadened the therapeutic choice and increased the chances of providing optimum arthritis control, but require careful assessment of the possibilities for unwanted drug effects when long-term therapy is required. A review of the literature on the gastrointestinal effects of the promising newer NSAIs, as compared with the older agents, aspirin, indomethacin, and phenylbutazone, is presented, highlighting animal toxicology and human adverse reaction surveillance data and the evidence for various suggested pathophysiological mechanisms.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. J Rheumatol. 1976;2:71-5 - PubMed
    1. Ann Rheum Dis. 1967 Nov;26(6):560-1 - PubMed
    1. Scand J Rheumatol Suppl. 1976;1976(0):123-7 - PubMed
    1. Drug Ther Bull. 1969 Apr 25;7(9):35-6 - PubMed
    1. Drugs. 1976;11(1):36-44 - PubMed

Publication types

MeSH terms