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. 2023 May 17;19(827):972-974.
doi: 10.53738/REVMED.2023.19.827.972.

[Long COVID : neurological aspects]

[Article in French]
Anthony Nuber-Champier  1   2 , Philippe Voruz  1   2   3 , Alexandre Cionca  1 , Isabele Jacot De Alcântara  1 , Julie Anne Péron  1   2 , Frédéric Assal  2   3
Affiliations

[Long COVID : neurological aspects]

[Article in French]
Anthony Nuber-Champier et al. Rev Med Suisse. .

Abstract
in English, French

The study of post-COVID-19 symptomatology revealed a first wave of post-acute (persistence of symptoms less than 3 months) neurocognitive symptoms. However, some of these symptoms worsened, while others improved. To our knowledge, these symptoms may persist for up to 1 to 2 years after infection. The intensity, variability and persistence of neurocognitive symptoms may rise the hypotheses of accelerated neurodegenerative processes, as well as neuropsychiatric and/or genetic vulnerabilities that are still poorly understood. Moreover, the multi-organ manifestations of post-COVID-19 symptoms remind us of the importance of promoting an interdisciplinary perspective at both clinical and fundamental levels. Finally, many social and economic issues parallel to the neuropathological consequences remain to be investigated.

L’étude de la symptomatologie post-Covid-19 a permis de mettre en évidence une première vague de symptômes neurocognitifs postaigus (persistance des symptômes inférieurs à 3 mois). Certains se sont aggravés, tandis que d’autres se sont améliorés. Ils peuvent perdurer jusqu’à 1 à 2 ans après l’infection. L’intensité, la variabilité et la persistance des symptômes neurocognitifs pourraient suggérer des hypothèses d’accélération de processus neurodégénératifs et des vulnérabilités neuropsychiatriques et/ou génétiques encore mal comprises. De plus, les manifestations multi-organiques des symptômes post-Covid-19 nous rappellent l’importance de promouvoir une perspective multidisciplinaire sur les plans clinique et fondamental. Finalement, de nombreuses questions sociales et économiques parallèles aux conséquences neuropathologiques restent à investiguer.

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Conflict of interest statement

Les auteurs n’ont déclaré aucun conflit d’intérêts en relation avec cet article.

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