Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 Jan-Feb;33(1):54-56.
doi: 10.4103/ijn.IJN_564_20. Epub 2022 Dec 26.

Crystal-Induced Lower GI Necrosis in a Posttransplant Recipient with Diverticular Disease

Affiliations
Case Reports

Crystal-Induced Lower GI Necrosis in a Posttransplant Recipient with Diverticular Disease

Maithrayie Kumaresan et al. Indian J Nephrol. 2023 Jan-Feb.

Abstract

We report the case of a 67-year-old male kidney transplant recipient for 12 years with sodium polystyrene sulfonate crystal-induced ileocecal colitis. He had adult polycystic kidney disease with associated colonic diverticular disease. Here, we describe how a potentially fatal complication of colonic perforation was averted with appropriate investigations and management.

Keywords: Hyperkalemia; ileocecal colitis; sodium polystyrene sulfonate crystals.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Gastrointestinal biopsy
Figure 2
Figure 2
Colonoscopy

References

    1. McGowan CE, Saha S, Chu G, Resnick MB, Moss SF. Intestinal necrosis due to sodium polystyrene sulfonate-(Kayexalate) in sorbitol. South Med J. 2009;102:493–7. - PMC - PubMed
    1. Almulhim AS, Hall E, Mershid Al Rehaili B, Almulhim AS. Sodium polystyrene sulfonate induced intestinal necrosis;A case report. Saudi Pharm J. 2018;26:771–4. - PMC - PubMed
    1. Gruy-Kapral C, Emmett M, Santa Ana CA, Porter JL, Fordtran JS, Fine KD. Effect of single dose resin-cathartic therapy on serum potassium concentration in patients with end-stage renal disease. J-Am Soc Nephrol. 1998;9:1924–30. - PubMed
    1. Sukri L, DiChiacchio L, Wasicek PJ, Kavic SM. Small bowel necrosis and perforation due to sodium polystyrene sulfonate in the setting of graft versus host disease and fulminant Clostridium difficile infection. J-Surg Case Rep. 2020;2020:rjaa253. - PMC - PubMed
    1. Harel Z, Harel S, Shah PS, Wald R, Perl J, Bell CM. Gastrointestinal adverse events with sodium polystyrene sulfonate-(Kayexalate) use:A-systematic review. Am J Med. 2013;126:264. e9-24. - PubMed

Publication types