Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 May 18;19(5):e1011361.
doi: 10.1371/journal.ppat.1011361. eCollection 2023 May.

Can we microbe-manage our vitamin acquisition for better health?

Affiliations

Can we microbe-manage our vitamin acquisition for better health?

Jana Nysten et al. PLoS Pathog. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. The role of gut microbiota in vitamin production.
Humans acquire vitamins through their diet and the microbiota in the large intestine, which can produce up to 30% of the recommended daily intake of vitamin K and the B group vitamins. The excreted vitamins can be used to cross-feed other species or can be absorbed by the host. Besides vitamin secretion, commensals in the GI tract can convert dietary vitamin A into active vitamin A metabolites, which are important for maintaining epithelial homeostasis and immune function. Created with BioRender.com. GI, gastrointestinal; IgA, immunoglobulin A; IL-17, interleukin 17; Th17, T-helper 17.

References

    1. Hooper LV, Wong MH, Thelin A, Hansson L, Falk PG, Gordon JI. Molecular analysis of commensal host-microbial relationships in the intestine. Science. 2001;291(5505):881–884. Epub 2001/02/07. doi: 10.1126/science.291.5505.881 . - DOI - PubMed
    1. Geuking MB, Cahenzli J, Lawson MA, Ng DC, Slack E, Hapfelmeier S, et al. Intestinal bacterial colonization induces mutualistic regulatory T cell responses. Immunity. 2011;34(5):794–806. Epub 2011/05/21. doi: 10.1016/j.immuni.2011.03.021 . - DOI - PubMed
    1. Niu W, Yang F, Fu Z, Dong Y, Zhang Z, Ju J. The role of enteric dysbacteriosis and modulation of gut microbiota in the treatment of inflammatory bowel disease. Microb Pathog. 2022;165:105381. Epub 2022/01/03. doi: 10.1016/j.micpath.2021.105381 . - DOI - PubMed
    1. Mosegaard S, Dipace G, Bross P, Carlsen J, Gregersen N, Olsen RKJ. Riboflavin Deficiency-Implications for General Human Health and Inborn Errors of Metabolism. Int J Mol Sci. 2020;21(11). Epub 2020/06/03. doi: 10.3390/ijms21113847 ; PubMed Central PMCID: PMC7312377. - DOI - PMC - PubMed
    1. Hill MJ. Intestinal flora and endogenous vitamin synthesis. Eur J Cancer Prev. 1997;6:S43–S45. Epub 1997/03/01. doi: 10.1097/00008469-199703001-00009 . - DOI - PubMed

Publication types