Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2023 Sep 8;46(9):zsad085.
doi: 10.1093/sleep/zsad085.

Stimulating hypocretin receptors improves sleepiness and vigilance in idiopathic hypersomnia: lessons from a proof of concept study

Affiliations
Editorial

Stimulating hypocretin receptors improves sleepiness and vigilance in idiopathic hypersomnia: lessons from a proof of concept study

Isabelle Arnulf et al. Sleep. .
No abstract available

PubMed Disclaimer

Comment on

Similar articles

References

    1. Mignot E, Bogan R, Emsellem H, et al. . Safety and pharmacodynamics of a single infusion of danavorexton in adults with idiopathic hypersomnia. Sleep. 2023;46(9):zsad049. doi: 10.1093/sleep/zsad049 - DOI - PMC - PubMed
    1. Evans R, Kimura H, Alexander R, et al. . Orexin 2 receptor-selective agonist danavorexton improves narcolepsy phenotype in a mouse model and in human patients. Proc Natl Acad Sci U S A. 2022;119:e2207531119. doi: 10.1073/pnas.2207531119 - DOI - PMC - PubMed
    1. Evans R, Kimura H, Nakashima M, et al. . Orexin 2 receptor-selective agonist danavorexton (TAK-925) promotes wakefulness in non-human primates and healthy individuals. J Sleep Res. 2023:e13878. - PubMed
    1. Dauvilliers Y, Bogan RK, Arnulf I, Scammell TE, St Louis EK, Thorpy MJ.. Clinical considerations for the diagnosis of idiopathic hypersomnia. Sleep Med Rev. 2022;66:101709. doi: 10.1016/j.smrv.2022.101709 - DOI - PubMed
    1. Arnulf I, Leu-Semenescu S, Dodet P.. Precision medicine for idiopathic hypersomnia. Sleep Med Clin. 2022;17:379–398. doi: 10.1016/j.jsmc.2022.06.016 - DOI - PubMed

Substances