Stimulating hypocretin receptors improves sleepiness and vigilance in idiopathic hypersomnia: lessons from a proof of concept study
- PMID: 37200618
- PMCID: PMC10485564
- DOI: 10.1093/sleep/zsad085
Stimulating hypocretin receptors improves sleepiness and vigilance in idiopathic hypersomnia: lessons from a proof of concept study
Comment on
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Safety and pharmacodynamics of a single infusion of danavorexton in adults with idiopathic hypersomnia.Sleep. 2023 Sep 8;46(9):zsad049. doi: 10.1093/sleep/zsad049. Sleep. 2023. PMID: 36883238 Free PMC article. Clinical Trial.
References
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- Evans R, Kimura H, Nakashima M, et al. Orexin 2 receptor-selective agonist danavorexton (TAK-925) promotes wakefulness in non-human primates and healthy individuals. J Sleep Res. 2023:e13878. - PubMed
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