Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Mar 1;61(259):212-215.
doi: 10.31729/jnma.8092.

Chronic Liver Disease among Patients Admitted in the Department of Internal Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study

Affiliations

Chronic Liver Disease among Patients Admitted in the Department of Internal Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study

Sujan Chandra Poudel et al. JNMA J Nepal Med Assoc. .

Abstract

Introduction: Chronic liver disease with cirrhosis is a significant cause of morbidity and mortality not only in developed but also in developing countries. Many patients already develop complications before hospital admission and require intensive medical care during hospital treatment. The main objective of the study was to find out the prevalence of the chronic liver disease among patients admitted in the Department of Internal Medicine of a tertiary care centre.

Methods: A descriptive cross-sectional study was conducted among patients admitted to the Department of Internal Medicine of a tertiary care centre from 1 January 2022 to 31 March 2022. Ethical approval was obtained from the Ethical Review Board (Reference number: 2211202105). The patient admitted in the Department during the study period was included and those who do not gave consent were excluded. Convenience sampling method was used. Point estimate and 95% Confidence Interval were calculated.

Results: Out of 447 patients, the prevalence of chronic liver disease was 93 (20.8%) (17.04-24.56, 95% Confidence Interval). The mean age of the patients was 49.69±10.94 years and among them, males were 64 (68.82%).

Conclusions: The prevalence of the chronic liver disease among patients admitted to the Department of Internal Medicine of a tertiary care centre was lower than in other studies conducted in similar settings.

Keywords: alcoholic liver diseases; liver diseases; prevalence.

PubMed Disclaimer

Conflict of interest statement

None.

Figures

Figure 1
Figure 1. Underlying conditions of patients with chronic liver disease (n= 93).
Figure 2
Figure 2. Child-Turcotte-Pugh score of patients with chronic liver disease (n= 93).

References

    1. Sharma A, Nagalli S. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022. Jul 4, 2022. Jan 4, Chronic liver disease.https://www.ncbi.nlm.nih.gov/books/NBK554597/ Available from:
    1. Younossi ZM, Stepanova M, Afendy M, Fang Y, Younossi Y, Mir H, et al. Changes in the prevalence of the most common causes of chronic liver diseases in the United States from 1988 to 2008. Clin Gastroenterol Hepatol. 2011 Jun;9(6):524–30. doi: 10.1016/j.cgh.2011.03.020. - DOI - PubMed
    1. de Franchis R, Primignani M. Natural history of portal hypertension in patients with cirrhosis. Clin Liver Dis. 2001 Aug;5(3):645–63. doi: 10.1016/S1089-3261(05)70186-0. - DOI - PubMed
    1. Asrani SK, Devarbhavi H, Eaton J, Kamath PS. Burden of liver diseases in the world. J Hepatol. 2019 Jan;70(1):151–71. doi: 10.1016/j.jhep.2018.09.014. - DOI - PubMed
    1. Ruf A, Dirchwolf M, Freeman RB. From Child-Pugh to MELD score and beyond: Taking a walk down memory lane. Ann Hepatol. 2022 Jan-Feb;27(1):100535. doi: 10.1016/j.aohep.2021.100535. - DOI - PubMed

LinkOut - more resources