Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Jul 22;2(3):e109.
doi: 10.1097/PG9.0000000000000109. eCollection 2021 Aug.

Gastrointestinal Basidiobolomycosis in a Child: Unusual Fungal Infection Mimicking Eosinophilic Gastrointestinal Diseases-A Case Report and Review of the Literature

Affiliations
Case Reports

Gastrointestinal Basidiobolomycosis in a Child: Unusual Fungal Infection Mimicking Eosinophilic Gastrointestinal Diseases-A Case Report and Review of the Literature

Fat'hiya Al Harthy et al. JPGN Rep. .

Abstract

Gastrointestinal basidiobolomycosis (GIB) is unusual, rare, and emerging fungal infection. It is caused by Basidiobolus ranarum. Unlike other fungal infections, B ranarum affects immunocompetent individuals with potentially grave sequelae if unrecognized. GIB is difficult to be diagnosed due to unspecific clinical presentation. Diagnosis of basidiobolomycosis requires culture of B ranarum from tissue. Optimal management of GIB includes antifungal therapy alongside if necessary early surgery.

Keywords: Oman; fungal infection; gastrointestinal basidiobolomycosis.

PubMed Disclaimer

Conflict of interest statement

The authors report no conflict of interest. The authors report no conflict of interest.

Figures

FIGURE 1.
FIGURE 1.
Radiological images. A) Ultrasound of the abdomen showed circumferential wall thickening of the cecum with severely narrowed lumen. B) CT scan of the abdomen with contrast (axial and coronal images) showed marked wall thickening of cecum (arrow) up to the splenic flexure (small arrow).
FIGURE 2.
FIGURE 2.
EGD and colonoscopy. A) Normal esophagus, (B) normal colon, (C) normal terminal ileum. EGD = esophagogastroduodenoscopy.
FIGURE 3.
FIGURE 3.
Intermediate power view (×20) showing gastric (A) and colonic (B) mucosa with numerous eosinophils in the lamina propria. Intermediate power view (×20) showing the typical morphology of Basidiobolus fungi (C).

References

    1. Pezzani MD, Di Cristo V, Parravicini C, et al. Gastrointestinal basidiobolomycosis: an emerging mycosis difficult to diagnose but curable. Case report and review of the literature. Travel Med Infect Dis. 2019; 31:101378. - PubMed
    1. Shreef K, Saleem M, Saeedd MA, et al. Gastrointestinal basidiobolomycosis: an emerging, and a confusing, disease in children (a multicenter experience). Eur J Pediatr Surg. 2018; 28:194–199. - PubMed
    1. Kurteva E, Bamford A, Cross K, et al. Colonic basidiobolomycosis—an unusual presentation of eosinophilic intestinal inflammation. Front Pediatr. 2020; 8:142. - PMC - PubMed
    1. Balkhair A, Al Wahaibi A, Al-Qadhi H, et al. Gastrointestinal basidiobolomycosis: beware of the great masquerade a case report. IDCases. 2019; 18:e00614. - PMC - PubMed
    1. Omar Takrouni A, Heitham Schammut M, Al-Otaibi M, et al. Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer. BMJ Case Rep. 2019; 12:e225054. - PMC - PubMed

Publication types