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Case Reports
. 2021 Aug 5;2(3):e091.
doi: 10.1097/PG9.0000000000000091. eCollection 2021 Aug.

Hereditary Angioedema Post-liver Transplant

Yusriya Al Rawahi  1   2 , Melanie Wong  3 , Michael Stormon  1
Affiliations
Case Reports

Hereditary Angioedema Post-liver Transplant

Yusriya Al Rawahi et al. JPGN Rep. .

Abstract

Liver transplantation is the standard of care in managing different types of liver disorders as well as a variety of inborn errors of metabolism. In the latter scenario, the liver-based enzyme abnormality is corrected by transplantation. Although rare, liver transplantation may result in the transmission of an inborn error of metabolism to the recipient. The present report describes the development of acquired hereditary angioedema likely following liver transplantation, with notable improvement with the initiation of C1 esterase inhibitor replacement therapy. This case report describes another example of a hepatic synthesis defect that, although rare, but can be acquired from donor's livers.

Keywords: Hereditary angioedema; cholestatic liver disease; inborn errors of metabolism.

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Conflict of interest statement

The authors report no conflicts of interest.

Figures

FIGURE 1.
FIGURE 1.
Improvement of liver transaminases with initiation of C1-INH therapy and the worsening after ceasing the C1-INH therapy. C1-INH, C1 esterase inhibitor.
See this image and copyright information in PMC

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