Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 May 3;25(6):291.
doi: 10.3892/etm.2023.11990. eCollection 2023 Jun.

COVID‑19 vaccination in liver transplant recipients (Review)

Affiliations
Review

COVID‑19 vaccination in liver transplant recipients (Review)

Aikaterini Gkoufa et al. Exp Ther Med. .

Abstract

Severe acute respiratory syndrome coronavirus 2 (Sars-CoV-2) infection has significantly affected immunocompromised individuals and subsequently, liver transplant recipients (LTRs). Early in the course of pandemic, this vulnerable population was prioritized for vaccination, after obtaining encouraging data about the vaccination benefits on disease severity and mortality. As the published knowledge was mainly supported from studies which were limited to the healthy population, the present review summarizes the data from the literature on coronavirus disease 2019 (COVID-19) vaccination in LTRs and the available vaccination guidelines of international societies. The COVID-19 vaccination of LTRs is strongly recommended as a safe and effective measure in order to prevent severe disease and mortality.

Keywords: coronavirus disease 2019; coronavirus disease 2019 vaccine; liver transplant; vaccination.

PubMed Disclaimer

Conflict of interest statement

DAS is the Editor-in-Chief for the journal, but had no personal involvement in the reviewing process, or any influence in terms of adjudicating on the final decision, for this article. The other authors declare that they have no competing interests.

Similar articles

Cited by

References

    1. Becchetti C, Gschwend SG, Dufour JF, Banz V. COVID-19 in liver transplant recipients: A systematic review. J Clin Med. 2021;10(4015) doi: 10.3390/jcm10174015. - DOI - PMC - PubMed
    1. Sripongpun P, Pinpathomrat N, Bruminhent J, Kaewdech A. Coronavirus disease 2019 vaccinations in patients with chronic liver disease and liver transplant recipients: An update. Front Med (Lausanne) 2022;9(924454) doi: 10.3389/fmed.2022.924454. - DOI - PMC - PubMed
    1. Azzi Y, Bartash R, Scalea J, Loarte-Campos P, Akalin E. COVID-19 and solid organ transplantation: A review article. Transplantation. 2021;105:37–55. doi: 10.1097/TP.0000000000003523. - DOI - PubMed
    1. Raja MA, Mendoza MA, Villavicencio A, Anjan S, Reynolds JM, Kittipibul V, Fernandez A, Guerra G, Camargo JF, Simkins J, et al. COVID-19 in solid organ transplant recipients: A systematic review and meta-analysis of current literature. Transplant Rev (Orlando) 2021;35(100588) doi: 10.1016/j.trre.2020.100588. - DOI - PMC - PubMed
    1. Goldman JD, Robinson PC, Uldrick TS, Ljungman P. COVID-19 in immunocompromised populations: Implications for prognosis and repurposing of immunotherapies. J Immunother Cancer. 2021;9(e002630) doi: 10.1136/jitc-2021-002630. - DOI - PMC - PubMed