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Randomized Controlled Trial
. 2023 May 19;23(1):96.
doi: 10.1186/s12894-023-01270-1.

Concerns about stone free rate and procedure events of percutaneous nephrolithotripsy (PCNL) for 2-4 cm kidney stones by standard-PCNL vs mini-PCNL- comparative randomised study

Mohamed Wishahi  1 , Ahmed El Feel  2 , Amr Elkhouly  3 , Abdullah Fahmy  3 , Mamdouh Roshdy  3 , Ahmed G Elbaz  3 , Ahmed I Kamel  3 , Mohamed Badawy  3 , Khaled Elesaily  3 , Samir Eldahshan  3 , Ayman Ali  3 , Ahmed Meheina  3 , Mohamed Abdelwahed  2
Affiliations
Randomized Controlled Trial

Concerns about stone free rate and procedure events of percutaneous nephrolithotripsy (PCNL) for 2-4 cm kidney stones by standard-PCNL vs mini-PCNL- comparative randomised study

Mohamed Wishahi et al. BMC Urol. .

Abstract

Background: To compare the efficacy and safety of standard percutaneous nephrolithotomy (PCNL) with mini- PCNL for kidney stones 2-4 cm.

Methods: Eighty patients were enrolled in a comparative study, they were randomly divided into mini-PCNL group (n = 40) and standard-PCNL (n = 40). Demographic characteristics, perioperative events, complications, stone free rate (SFR) were reported.

Results: Both groups showed no significant difference in clinical data about age, stone location, back pressure changes, and body mass index. The mean operative time was (95 ± 17.9 min) in mini-PCNL, and (72.1 ± 14.9 min). Stone free rate were 80% and 85% in mini-PCNL and standard-PCNL respectively. Intra-operative complications, post-operative need for analgesia, hospital stay were significantly higher in standard-PCNL compared to mini-PCNL (85% vs. 80%). The study followed CONSORT 2010 guidelines for reporting parallel group randomization.

Conclusion: Mini-PCNL is an effective and safe treatment of kidney stones 2-4 cm, it has the advantage over standard-PCNL being has less intra-operative events, less post-operative analgesia, shorter hospital stay, while operative time and stone free rate are comparable when considering multiplicity, hardness, and site of stones.

Keywords: Kidney stones; Mini percutaneous nephrolithotomy; Percutaneous nephrolithotomy; Renal stones; Stone free rate.

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Conflict of interest statement

The authors have no competing interests to declare that are relevant to the content of this article.

Figures

Fig. 1
Fig. 1
Operative and postoperative outcome in mini-PCNL vs standard-PCNL: (A) Showing difference in Operative time and stone extraction time between mini-PCNL vs mini-PCNL. (B) Showing the need for postoperative analgesics among mini-PCNL vs standard-PCNL. (C) Showing hospital stay (days) among mini-PCNL vs standard-PCNL
See this image and copyright information in PMC

References

    1. Wright A, Rukin N, Smith D, De la Rosette J, Somani BK. (2016) 'Mini, ultra, micro’ - nomenclature and cost of these new minimally invasive percutaneous nephrolithotomy (PCNL) techniques Ther Adv Urol. 8(2):142–6. doi: 10.1177/1756287215617674. Epub 2015 Nov 26. PMID: 27034726; PMCID: PMC4772355. - PMC - PubMed
    1. Mishra S, Sharma R, Garg C, Kurien A, Sabnis R, Desai M. (2011). Prospective comparative study of miniperc and standard PNL for treatment of 1 to 2 cm size renal stone. BJU Int. 108(6):896-9; discussion 899–900. doi: 10.1111/j.1464-410X.2010.09936.x. Epub 2011 Apr 8. PMID: 21477212. - PubMed
    1. Hu G, Guo Z, Liu H, Luo M, Liu M, Lai P, Zhang H, Yuan J, Yao X, Zheng J, Xu Y. A novel minimally invasive percutaneous nephrolithotomy technique: safety and efficacy report. Scand J Urol. 2015;49(2):174–80. doi: 10.3109/21681805.2014.961545. - DOI - PubMed
    1. Jackman SV, Docimo SG, Cadeddu JA, Bishoff JT, Kavoussi LR, Jarrett TW. The "mini-perc" technique: a less invasive alternative to percutaneous nephrolithotomy. World J Urol. 1998;16(6):371–4. doi: 10.1007/s003450050083. - DOI - PubMed
    1. Li MM, Yang HM, Liu XM, Qi HG, Weng GB. Retrograde intrarenal surgery vs miniaturized percutaneous nephrolithotomy to treat lower pole renal stones 1.5–2.5 cm in diameter. World J Clin Cases. 2018;6(15):931–5. doi: 10.12998/wjcc.v6.i15.931. - DOI - PMC - PubMed

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