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Case Reports
. 2023 May 20;23(1):338.
doi: 10.1186/s12879-023-08308-7.

Salmonella Durban meningitis: case report and genomics study

Christelle Nanga Diasi  1   2 , Pieter-Jan Ceyssens  3 , Alexandra Vodolazkaia  4 , Marina Mukovnikova  4 , Sarah Dorval  1   5 , Olivia Bauraind  1   6 , Wesley Mattheus  7
Affiliations
Case Reports

Salmonella Durban meningitis: case report and genomics study

Christelle Nanga Diasi et al. BMC Infect Dis. .

Abstract

Background: Bacterial meningitis caused by non-typhoid Salmonella can be a fatal condition which is more common in low and middle-income countries.

Case presentation: We report the case of a Salmonella meningitis in a Belgian six-month old male infant. The first clinical examination was reassuring, but after a few hours, his general state deteriorated. A blood test and a lumbar puncture were therefore performed. The cerebrospinal fluid analysis was compatible with a bacterial meningitis which was later identified by the NRC (National Reference Center) as Salmonella enterica serovar Durban.

Conclusions: In this paper, we present the clinical presentation, genomic typing, and probable sources of infection for an unusually rare serovar of Salmonella. Through an extended genomic analysis, we established its relationship to historical cases with links to Guinea.

Keywords: Bacterial infection; Meningitis; Non-typhoid Salmonella; Paediatrics; Salmonella Durban.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Minimum Spanning Tree using cgMLST data (EnteroBase scheme, https://enterobase.warwick.ac.uk/) of S. enterica serovar Durban of this case report and historical cases isolated from patients in Belgium between 2014 and 2021. Each node represents an isolate, with allelic differences indicated as branch length. Isolates with travel history to Guinea are highlighted in yellow. (epi = disease episode)
Fig. 2
Fig. 2
Brain magnetic resonance imaging showing purulent suffusion on day 2 during the first admission
See this image and copyright information in PMC

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