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Editorial
. 2023 Jul 5;28(7):e588-e589.
doi: 10.1093/oncolo/oyad130.

Regarding "Neoadjuvant Versus Adjuvant Chemotherapy for Resectable Metastatic Colon Cancer in Non-academic and Academic Programs"

I-Hsuan Su  1 , Jennifer L Lund  1   2 , Charles E Gaber  3 , Hanna K Sanoff  2   4 , Paula D Strassle  5 , Emilie D Duchesneau  1   2
Affiliations
Editorial

Regarding "Neoadjuvant Versus Adjuvant Chemotherapy for Resectable Metastatic Colon Cancer in Non-academic and Academic Programs"

I-Hsuan Su et al. Oncologist. .

Abstract

This letter to the editor expresses concerns related to immortal time bias that may partially account for recently published study results.

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Conflict of interest statement

The authors indicated no financial relationships.

Figures

Figure 1.
Figure 1.
Time from date of diagnosis to surgery in patients classified as undergoing neoadjuvant chemotherapy and time from date of diagnosis to initiation of chemotherapy in those classified as undergoing adjuvant chemotherapy, among colon cancer patients with single lung or liver metastasis in the NCDB.
See this image and copyright information in PMC

Comment in

Comment on

References

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    1. Suissa S. Immortal time bias in observational studies of drug effects. Pharmacoepidemiol Drug Saf. 2007;16(3):241-249. 10.1002/pds.1357. - DOI - PubMed
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    1. Hernán MA, Wang W, Leaf DE.. Target trial emulation: a framework for causal inference from observational data. JAMA. 2022. 10.1001/JAMA.2022.21383 - DOI - PubMed

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