Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Jun;29(6):1-9.
doi: 10.3201/eid2906.221648.

One Health Approach for Reporting Veterinary Carbapenem-Resistant Enterobacterales and Other Bacteria of Public Health Concern

Kate KuKanich, Amy Burklund, Rob McGaughey, Nancy Muturi, Sasha Thomason, M M Chengappa, Ingrid Garrison, Bryna Stacey, Shuping Zhang, Tamara Gull

One Health Approach for Reporting Veterinary Carbapenem-Resistant Enterobacterales and Other Bacteria of Public Health Concern

Kate KuKanich et al. Emerg Infect Dis. 2023 Jun.

Abstract

A carbapenem-resistant Enterobacterales outbreak at a veterinary teaching hospital in the United States increased urgency for improved communication among diagnostic laboratories, public health authorities, veterinarians, and pet owners. Kansas State University, University of Missouri, Kansas Department of Health and Environment, and Veterinary Laboratory Investigation and Response Network created a surveillance, storage, and reporting protocol for veterinary antimicrobial-resistant bacteria; determined frequency of those bacteria in companion animals during 2018-2021; and created educational flyers for veterinarians and pet owners. We recommend a One Health strategy to create efficient surveillance programs to identify and report antimicrobial-resistant bacteria and educate veterinarians and pet owners about transmission risks.

Keywords: Enterobacterales; Kansas; MRSA and other staphylococci; Missouri; One Health; Pseudomonas; Staphylococcus aureus; Staphylococcus pseudintermedius; United States; antimicrobial resistance; bacteria; carbapenem-resistant; carbapenem-resistant Enterobacterales; companion animals; educational flyers; public health; zoonoses.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Numbers of carbapenem-resistant Pseudomonas aeruginosa isolates from canids in study of One Health approach for reporting veterinary carbapenem-resistant Enterobacterales and other bacteria of public health concern, United States, January 1, 2018–December 31, 2021. Black bars indicate isolates from Kansas State Veterinary Diagnostic Laboratory, green bars isolates from the University of Missouri Veterinary Medical Diagnostic Laboratory. At Kansas State Veterinary Diagnostic Laboratory, the total numbers of P. aeruginosa isolates from dogs were 159 in 2018, 150 in 2019, 146 in 2020, and 178 in 2021. At University of Missouri Veterinary Medical Diagnostic Laboratory, the total numbers of P. aeruginosa isolates from dogs were 151 in 2018, 169 in 2019, 166 in 2020, and 163 in 2021.
Figure 2
Figure 2
Numbers of MRSA and methicillin-resistant Staphylococcus pseudintermedius isolates from canids in study of One Health approach for reporting veterinary carbapenem-resistant Enterobacterales and other bacteria of public health concern, United States, January 1, 2018–December 31, 2021. Numbers and percentages of antimicrobial-resistant isolates (compared with all canine Staphylococcus spp. isolates) per year for each laboratory are shown. Kansas State Veterinary Diagnostic Laboratory isolates are indicated by black bars (MRSA) and green bars (methicillin-resistant S. pseudintermedius); University of Missouri Veterinary Medical Diagnostic Laboratory isolates are indicated by blue bars (MRSA) and green bars (methicillin-resistant S. pseudintermedius). Total numbers of Staphylococcus spp. from canids at Kansas State Veterinary Diagnostic Laboratory were 536 in 2018, 578 in 2019, 530 in 2020, and 680 in 2021. Total numbers of Staphylococcus spp. isolates from canids at University of Missouri Veterinary Medical Diagnostic Laboratory were 563 in 2018, 532 in 2019, 661 in 2020, and 608 in 2021.
Figure 3
Figure 3
Numbers of MRSA and methicillin-resistant Staphylococcus pseudintermedius isolates from felids in study of One Health approach for reporting veterinary carbapenem-resistant Enterobacterales and other bacteria of public health concern, United Stated, January 1, 2018–December 31, 2021. Numbers and percentages of antimicrobial-resistant isolates (compared with all feline Staphylococcus spp. isolates) per year for each laboratory are shown. Kansas State Veterinary Diagnostic Laboratory isolates are indicated by black bars (MRSA) and red bars (methicillin-resistant S. pseudintermedius); University of Missouri Veterinary Medical Diagnostic Laboratory isolates are indicated by blue bars (MRSA) and green bars (methicillin-resistant S. pseudintermedius). Total numbers of Staphylococcus spp. isolates from felids at Kansas State Veterinary Diagnostic Laboratory were 54 in 2018, 60 in 2019, 55 in 2020, and 79 in 2021. Total numbers of Staphylococcus spp. isolates from felids at University of Missouri Veterinary Medical Diagnostic Laboratory were 63 in 2018, 60 in 2019, 67 in 2020, and 85 in 2021.
See this image and copyright information in PMC

References

    1. Belas A, Menezes J, Gama LT, Pomba C. Sharing of clinically important antimicrobial resistance genes by companion animals and their human household members. Microb Drug Resist. 2020;26:1174–85. 10.1089/mdr.2019.0380 - DOI - PubMed
    1. Cuny C, Witte W. MRSA in equine hospitals and its significance for infections in humans. Vet Microbiol. 2017;200:59–64. 10.1016/j.vetmic.2016.01.013 - DOI - PubMed
    1. Fernandes MR, Sellera FP, Moura Q, Carvalho MPN, Rosato PN, Cerdeira L, et al. Zooanthroponotic transmission of drug-resistant Pseudomonas aeruginosa, Brazil. Emerg Infect Dis. 2018;24:1160–2. 10.3201/eid2406.180335 - DOI - PMC - PubMed
    1. Frank LA, Kania SA, Kirzeder EM, Eberlein LC, Bemis DA. Risk of colonization or gene transfer to owners of dogs with meticillin-resistant Staphylococcus pseudintermedius. Vet Dermatol. 2009;20:496–501. 10.1111/j.1365-3164.2009.00826.x - DOI - PubMed
    1. Grönthal T, Österblad M, Eklund M, Jalava J, Nykäsenoja S, Pekkanen K, et al. Sharing more than friendship - transmission of NDM-5 ST167 and CTX-M-9 ST69 Escherichia coli between dogs and humans in a family, Finland, 2015. Euro Surveill. 2018;23:1700497. 10.2807/1560-7917.ES.2018.23.27.1700497 - DOI - PMC - PubMed

Publication types

LinkOut - more resources