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. 1986 Jun;27(6):648-51.
doi: 10.1136/gut.27.6.648.

Outpatient endoscopic survey of smoking and peptic ulcer

C C Ainley, I C Forgacs, P W Keeling, R P Thompson

Outpatient endoscopic survey of smoking and peptic ulcer

C C Ainley et al. Gut. 1986 Jun.

Abstract

A survey of the smoking habits of 1217 outpatients undergoing upper gastrointestinal endoscopy was carried out over an 18 month period. Six hundred and twenty four were current smokers, 248 ex-smokers and 345 non-smokers. 11.9% of smokers had gastric ulcers, 7.7% of ex-smokers (p less than 0.025) and 4.6% of non-smokers (p less than 0.001). 2.8% of smokers had duodenal ulcers, 6.8% of ex-smokers (p less than 0.01) and 6.1% of non-smokers (p less than 0.001). There was a dose response effect between the number of cigarettes smoked and duodenal and gastric ulceration. Gastric cancer was also more frequent in smokers than non-smokers (p less than 0.01), but macroscopic oesophagitis less frequent (p less than 0.001). The results confirm the association between smoking and peptic ulcer.

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