Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1977 Sep;32(3):221-6.

Phenobarbital in prophylaxis of neonatal jaundice. A control trial of two regimens

B Salle, P Pasquer, C Desebbe, J M Rouzioux, B Barouty
  • PMID: 372140
Clinical Trial

Phenobarbital in prophylaxis of neonatal jaundice. A control trial of two regimens

B Salle et al. Helv Paediatr Acta. 1977 Sep.

Abstract

The prevention of neonatal hyperbilirubinemia by phenobarbital is widely used in many countries. However, dose and period of administration vary according to authors, as the dose-effect relation is not known and since little research in pharmacokinetics of phenobarbital has been done so far. In the present study we compared the effect on serum bilirubin of a single injection of 10 mg/kg body weight and of a prolonged administration of 10 mg/kg/day during 3 days in premature and full-term newborn infants. The single injection had the same effect as the prolonged administration, provided it was given within 12 h after birth.

PubMed Disclaimer

Publication types