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Case Reports
. 2023 Apr 18;15(4):e37762.
doi: 10.7759/cureus.37762. eCollection 2023 Apr.

Surgical Treatment of Penile Verrucous Squamous Cell Carcinoma in an HIV-Infected Patient: A Case Report

Yacoub A Okieh  1   2 , Craig Aurtz Tombet  1   2 , Anouar El Moudane  1   2 , Yousef Kouiss  1   2 , Ali Barki  1   2
Affiliations
Case Reports

Surgical Treatment of Penile Verrucous Squamous Cell Carcinoma in an HIV-Infected Patient: A Case Report

Yacoub A Okieh et al. Cureus. .

Abstract

Although uncommon, penile carcinoma can be a debilitating disease with various causes, and cancer is a significant contributor to morbidity and mortality in individuals infected with HIV. Verrucous carcinoma, a subtype of epidermoid carcinoma, is typically slow-growing and has a low propensity to metastasize. We present a case study of a 55-year-old HIV-positive patient with a massive squamous cell carcinoma of the penis that had been developing for over two years. To treat the condition, the patient underwent a total penectomy, perineal urethrostomy, and bilateral inguinal lymphadenectomy.

Keywords: human immunodeficiency virus; infection; surgery; total penectomy; verrucous carcinoma.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Penile mass on physical examination.
Figure 2
Figure 2. CT scan of the thorax, abdomen, and pelvis revealed bilateral inguinal lymphadenopathies.
Figure 3
Figure 3. The surgical area after total penectomy and perineal urethrostomy were performed.
Figure 4
Figure 4. H&E-stained sections of the defects revealed squamous cell carcinoma with signs of keratinization.
See this image and copyright information in PMC

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