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Review
. 2023 May 22;15(1):25.
doi: 10.1186/s13099-023-00551-2.

Management of dyspepsia and Helicobacter pylori infection: the 2022 Indonesian Consensus Report

Ari Fahrial Syam  1 , Muhammad Miftahussurur  2   3 , Dadang Makmun  4 , Murdani Abdullah  4 , Abdul Aziz Rani  4 , Gontar Alamsyah Siregar  5 , Marcellus Simadibrata  4 , Nasrul Zubir  6 , I Dewa Nyoman Wibawa  7 , Hery Djagat Purnomo  8 , Chudahman Manan  4 , Dharmika Djojoningrat  4 , Achmad Fauzi  4 , Kaka Renaldi  4 , Hasan Maulahela  4 , Amanda Pitarini Utari  4 , Rabbinu Rangga Pribadi  4 , Virly Nanda Muzellina  4 , Saskia Aziza Nursyirwan  4 , Muhammad Firhat Idrus  4 , Ruswhandi Ruswhandi  9 , Titong Sugihartono  10 , Muhammad Begawan Bestari  11 , Putut Bayupurnama  12 , Triyanta Yuli Pramana  13 , Bogi Pratomo Wibowo  14 , Achmad Fuad Bakry  15 , Fardah Akil  16 , Andi Muhammad Luthfi Parewangi  16 , Haris Widita  17 , I Ketut Mariadi  7 , Ignatia Sinta Murti  18 , Ali Imron Yusuf  19 , Arles Arles  20 , Fauzi Yusuf  21 , Bradley Jimmy Waleleng  22 , Abimanyu Abimanyu  23 , Yustar Mulyadi  24 , Maria Inge Lucida  25 , Yudith Annisa Ayu Rezkhita  26   27 , Ricky Indra Alfaray  26   28 , Yoshio Yamaoka  28   29   30
Affiliations
Review

Management of dyspepsia and Helicobacter pylori infection: the 2022 Indonesian Consensus Report

Ari Fahrial Syam et al. Gut Pathog. .

Abstract

Dyspepsia still becomes a major challenge in upper gastrointestinal disease in Indonesia. This disease often correlated with Helicobacter pylori infection. However, the prevalence of this bacterium is generally low in Indonesia. Therefore, several considerations should be taken into consideration during the management of dyspepsia and H. pylori infection. "Management of dyspepsia and H. pylori infection in Indonesia: The Indonesian consensus report" comprises information gathered from 22 gastroenterology centers across Indonesia. The experts gathered to evolve a consensus, that consists of the statements, grades of recommendations, evidence levels, and rationales for the dyspepsia and H. pylori infection management for daily clinical practice. The report explains several aspects from the updated epidemiology information to comprehensive management therapy. After the experts worked together on all statements in the recommendations, the results are presented with the final agreement as a consensus to help clinicians in understanding, diagnosing, and treating dyspepsia and H. pylori infection patients in daily clinical practice in Indonesia.

Keywords: Dyspepsia; Helicobacter pylori infection; Human and illness; Indonesia; Management.

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Conflict of interest statement

The authors declare no competing interests.

The authors declare there is no potential competing interests.

Figures

Fig. 1
Fig. 1
Steps for assigning the quality of evidence until grade of recommendation
Fig. 2
Fig. 2
Algorithm for the diagnosis of uninvestigated dyspepsia
Fig. 3
Fig. 3
Algorithm for the management of dyspepsia
Fig. 4
Fig. 4
Locations of gastric biopsy recommended by the updated Sydney System. a Lesser curvature of the antrum; b greater curvature of the antrum; c lesser curvature of the body; d greater curvature of the body; and e incisura angularis [2]. Avoid taking biopsy specimens directly from the ulcer site
Fig. 5
Fig. 5
Algorithm of H. pylori antibiotic therapy. a In case of failure, an antibiotic susceptibility test is strongly recommended. The next antibiotic regimen should be chosen based on the results of the antibiotic susceptibility test. b Bali is an area with high clarithromycin resistance (≥ 15%). c Areas with high resistance to levofloxacin (≥ 15%) are Bali, Java, Kalimantan, Papua, Sulawesi, Sumatra, and Timor
See this image and copyright information in PMC

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