Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1986;84(4-6):383-6.
doi: 10.1007/BF00482967.

Demonstration of X chromatin in drumstick-like nuclear appendages of leukocytes by in situ hybridization on blood smears

Demonstration of X chromatin in drumstick-like nuclear appendages of leukocytes by in situ hybridization on blood smears

P F Hochstenbach et al. Histochemistry. 1986.

Abstract

An X chromosome specific nucleic acid probe was used to study the positions of the X chromosomes in leukocyte nuclei by in situ hybridization to smears of peripheral blood. This autoradiographic approach allowed the first direct demonstration of the presence of X chromosomal material in the drumstick-like structures of female polymorphonuclear leukocytes.

PubMed Disclaimer

Similar articles

Cited by

  • Genome organization in immune cells: unique challenges.
    Johanson TM, Chan WF, Keenan CR, Allan RS. Johanson TM, et al. Nat Rev Immunol. 2019 Jul;19(7):448-456. doi: 10.1038/s41577-019-0155-2. Nat Rev Immunol. 2019. PMID: 30926914 Review.
  • Can sex be determined from a blood smear?
    Brahimi M, Adda A, Lazreg H, Beliali H, Osmani S, Bekadja MA. Brahimi M, et al. Turk J Haematol. 2013 Mar;30(1):53-7. doi: 10.4274/tjh.2011.0015. Epub 2013 Mar 5. Turk J Haematol. 2013. PMID: 24385754 Free PMC article.

References

    1. Hum Genet. 1976 Mar 12;31(3):293-307 - PubMed
    1. Am J Hum Genet. 1984 Jul;36(4):769-76 - PubMed
    1. Hum Genet. 1980 Feb;53(2):131-43 - PubMed
    1. Lancet. 1964 Mar 14;1(7333):589-90 - PubMed
    1. Lancet. 1971 May 8;1(7706):973-4 - PubMed