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. 2023 Aug 1;48(8):697-698.
doi: 10.1097/RLU.0000000000004702. Epub 2023 Jun 10.

Real-Time Identification of Nodal Metastases With 99m Tc-Prostate-Specific Membrane Antigen-Based Radioguidance and Indocyanine Green Fluorescence Imaging in Primary Prostate Cancer Surgery-On the Road to Hybrid Image-Guided Surgery

Hilda A de Barros, Matthias N van Oosterom, Fijs W B van Leeuwen, Henk G van der Poel, Pim J van Leeuwen

Real-Time Identification of Nodal Metastases With 99m Tc-Prostate-Specific Membrane Antigen-Based Radioguidance and Indocyanine Green Fluorescence Imaging in Primary Prostate Cancer Surgery-On the Road to Hybrid Image-Guided Surgery

Hilda A de Barros et al. Clin Nucl Med. .

Abstract

Recent developments in image-guided prostate cancer surgery focus on extending prostate-specific membrane antigen-directed radioguidance with optical tumor detection using fluorescence, as radio- and fluorescence signals complement each other with in-depth detection and real-time visualization, respectively. As a step in this direction, we report here the integration of indocyanine green fluorescence imaging into a 99m Tc-prostate-specific membrane antigen-targeted radioguided surgery workflow.

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Conflict of interest statement

Conflicts of interest and sources of funding: none declared.

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