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Review
. 2024 Aug 1;154(2):391e-402e.
doi: 10.1097/PRS.0000000000010706. Epub 2023 May 23.

Clinically Important Pharmacologic Considerations for Wide-Awake Local Anesthesia No Tourniquet Hand Surgery

Lindsay Janes  1 , Sarvnaz Sepehripour  2 , Donald Lalonde  3
Affiliations
Review

Clinically Important Pharmacologic Considerations for Wide-Awake Local Anesthesia No Tourniquet Hand Surgery

Lindsay Janes et al. Plast Reconstr Surg. .

Abstract

Understanding the clinically important pharmacokinetics (what the body does to the drug) and pharmacodynamics (what the drug does to the body) of medications used in surgery will help surgeons use them more safely and effectively. The goal of this article is to provide an overview of these considerations for the 2 medications used in wide-awake local anesthesia with no tourniquet upper extremity surgery (ie, lidocaine and epinephrine) to establish a better understanding of lidocaine and epinephrine in tumescent local anesthesia, as well as adverse reactions and how to manage them.

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References

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