Angiotensin-Neprilysin Inhibition in Heart Failure With Preserved Ejection Fraction: You Win Some, You Lose Some
- PMID: 37220861
- DOI: 10.1016/j.jacc.2023.05.002
Angiotensin-Neprilysin Inhibition in Heart Failure With Preserved Ejection Fraction: You Win Some, You Lose Some
Keywords: angiotensin-neprilysin inhibition; clinical trials; heart failure with preserved ejection fraction; outcomes; win ratio.
Conflict of interest statement
Funding Support and Author Disclosures Dr Lavie has served as a speaker and consultant for AstraZeneca on their HF agent Farxiga. Dr Mehra has received travel support and consulting fees, paid to Brigham and Women’s Hospital, from Abbott; has received fees for serving on a steering committee from Janssen (Johnson & Johnson); has received fees for serving on a data and safety monitoring board from Mesoblast; has received consulting fees from Natera, Paragonix, Moderna, the Baim Institute of Clinical Research, and Broadview Ventures; and has received fees for serving as a scientific board member from NuPulseCV, Leviticus, Transmedics, and FineHeart. Dr Ventura has reported that he has no relationships relevant to the contents of this paper to disclose.
Comment on
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Angiotensin-Neprilysin Inhibition in Patients With Mildly Reduced or Preserved Ejection Fraction and Worsening Heart Failure.J Am Coll Cardiol. 2023 Jul 4;82(1):1-12. doi: 10.1016/j.jacc.2023.04.019. Epub 2023 May 21. J Am Coll Cardiol. 2023. PMID: 37212758 Clinical Trial.
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