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Case Reports
. 2023 May 23;16(5):e253880.
doi: 10.1136/bcr-2022-253880.

Sarcoidosis of the lacrimal gland: the prominence of the differential diagnosis

Guido Gabriele  1 , Flavia Cascino  2 , Linda Latini  2 , Paolo Gennaro  2
Affiliations
Case Reports

Sarcoidosis of the lacrimal gland: the prominence of the differential diagnosis

Guido Gabriele et al. BMJ Case Rep. .

Abstract

Sarcoidosis is a multisystem disease that can involve any organ; lungs, lymph nodes and skin are the most involved. Compatible clinical and imaging features, the identification of non-caseous granulomas on biopsy and the exclusion of other causes of granulomatous disorders help formulate the diagnosis of sarcoidosis. A bilateral symmetrical hilar lymphadenopathy together with the typical perilymphatic distribution of nodules is typically visible on high-resolution CT.The average age is 48 years. Ocular sarcoidosis is not rare, it is reported in 25% of cases. Half of the sarcoidosis patients resolve spontaneously; treatment is only indicated in cases with severe symptoms or signs of organ damage. Classical treatments are based on the use of corticosteroids and immunosuppressive therapies, sometimes combined.

Keywords: COVID-19; Interstitial lung disease; Oral and maxillofacial surgery.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Patient appearance before biopsy.
Figure 2
Figure 2
On the CT facial skeleton, a circle highlights an enlargement of the left lacrimal gland.
Figure 3
Figure 3
HRCT of the lung showing a sarcoidotic picture. HRCT, high-resolution CT.
Figure 4
Figure 4
Radiopharmaceutical fixation in the brain on PET-CT scan. PET, positron emission tomography.
Figure 5
Figure 5
Radiopharmaceutical fixation in the lungs on PET-CT scan. PET, positron emission tomography
See this image and copyright information in PMC

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