Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 May 24;39(8):207.
doi: 10.1007/s11274-023-03658-5.

Recent advances in the production, properties and applications of alginate oligosaccharides - a mini review

Li Li  1 , Jinju Jiang  2 , Zhong Yao  1 , Benwei Zhu  3
Affiliations
Review

Recent advances in the production, properties and applications of alginate oligosaccharides - a mini review

Li Li et al. World J Microbiol Biotechnol. .

Abstract

Alginate oligosaccharides (AOS) made from the degradation of alginate, to some extent, makes up for the poor solubility and bioavailability of alginate as a macromolecular substance and possess several beneficial biological activities that are absent in alginate. These properties include prebiotic, glycolipid regulatory, immunomodulatory, antimicrobial, antioxidant, anti-tumor, promoting plant growth and other activities. Consequently, AOS has significant potential for use in the agricultural, biomedical, and food industries, and has been the focus of research in the field of marine biological resources. This review comprehensively covers methods (physical, chemical, and enzymatic methods) for the production of AOS from alginate. More importantly, this paper reviews recent advances in the biological activity and potentially industrial and therapeutic applications of AOS, providing a reference for future research and applications of AOS.

Keywords: Alginate; Alginate lyase; Alginate oligosaccharides; Biological activity; Production.

PubMed Disclaimer

References

    1. Abd El-Mohdy HL (2017) Radiation-induced degradation of sodium alginate and its plant growth promotion effect. Arabian Journal of Chemistry, 10, S431-S438. Retrieved from < Go to ISI>://WOS:000399414100062
    1. Aida TM, Yamagata T, Watanabe M, Smith RL (2010) Depolymerization of sodium alginate under hydrothermal conditions. Carbohydr Polym 80(1):296–302. https://doi.org/10.1016/j.carbpol.2009.11.032 - DOI
    1. Aitouguinane M, Bouissil S, Mouhoub A, Rchid H, Fendri I, Abdelkafi S, Delattre C (2020) Induction of natural defenses in Tomato Seedlings by using Alginate and Oligoalginates derivatives extracted from moroccan Brown Algae. Mar Drugs 18(10). https://doi.org/10.3390/md18100521
    1. Amtzen MO, Pedersen B, Klau LJ, Stokke R, Oftebro M, Antonsen SG, Eijsink VGH (2021) Alginate Degradation: insights obtained through characterization of a thermophilic Exolytic Alginate Lyase. Appl Environ Microbiol, 87(6). doi:ARTN e02399-20. https://doi.org/10.1128/AEM.02399-20
    1. Balakrishnan B, Lesieur S, Labarre D, Jayakrishnan A (2005) Periodate oxidation of sodium alginate in water and in ethanol-water mixture: a comparative study. Carbohydr Res 340(7):1425–1429. https://doi.org/10.1016/j.carres.2005.02.028 - DOI - PubMed

LinkOut - more resources