Post-intensive care syndrome (PICS): recent updates

doi:10.1186/s40560-023-00670-7

Review

. 2023 May 23;11(1):23.

doi: 10.1186/s40560-023-00670-7.

Post-intensive care syndrome (PICS): recent updates

Stephanie L Hiser^{1

2

3}, Arooj Fatima^{4

5}, Mazin Ali^{4

5}, Dale M Needham^{6

4

5

7}

Affiliations

¹ Department of Health, Human Function, and Rehabilitation Sciences, The George Washington University, 2000 Pennsylvania Ave. NW, Suite 2000, Washington, DC, 20006, USA. stephanie.hiser@gwu.edu.
² Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA. stephanie.hiser@gwu.edu.
³ Outcomes After Critical Illness and Surgery (OACIS) Group, Johns Hopkins University, Baltimore, MD, USA. stephanie.hiser@gwu.edu.
⁴ Outcomes After Critical Illness and Surgery (OACIS) Group, Johns Hopkins University, Baltimore, MD, USA.
⁵ Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
⁶ Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
⁷ School of Nursing, Johns Hopkins University, Baltimore, MD, USA.

PMID: 37221567
PMCID: PMC10202754
DOI: 10.1186/s40560-023-00670-7

Review

Post-intensive care syndrome (PICS): recent updates

Stephanie L Hiser et al. J Intensive Care. 2023.

. 2023 May 23;11(1):23.

doi: 10.1186/s40560-023-00670-7.

Authors

Stephanie L Hiser^{1

2

3}, Arooj Fatima^{4

5}, Mazin Ali^{4

5}, Dale M Needham^{6

4

5

7}

Affiliations

¹ Department of Health, Human Function, and Rehabilitation Sciences, The George Washington University, 2000 Pennsylvania Ave. NW, Suite 2000, Washington, DC, 20006, USA. stephanie.hiser@gwu.edu.
² Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA. stephanie.hiser@gwu.edu.
³ Outcomes After Critical Illness and Surgery (OACIS) Group, Johns Hopkins University, Baltimore, MD, USA. stephanie.hiser@gwu.edu.
⁴ Outcomes After Critical Illness and Surgery (OACIS) Group, Johns Hopkins University, Baltimore, MD, USA.
⁵ Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
⁶ Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
⁷ School of Nursing, Johns Hopkins University, Baltimore, MD, USA.

PMID: 37221567
PMCID: PMC10202754
DOI: 10.1186/s40560-023-00670-7

Abstract

An increasing number of patients are surviving critical illness, but some experience new or worsening long-lasting impairments in physical, cognitive and/or mental health, commonly known as post-intensive care syndrome (PICS). The need to better understand and improve PICS has resulted in a growing body of literature exploring its various facets. This narrative review will focus on recent studies evaluating various aspects of PICS, including co-occurrence of specific impairments, subtypes/phenotypes, risk factors/mechanisms, and interventions. In addition, we highlight new aspects of PICS, including long-term fatigue, pain, and unemployment.

Keywords: Critical illness; Intensive care; Long-term outcomes.

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Conflict of interest statement

The authors declare no competing interests.

Figures

**Fig. 1**
Barriers to return to work after critical illness

See this image and copyright information in PMC

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References

1. Calvin JE, Habet K, Parrillo JE. Critical care in the United States who are we and how did we get here? Crit Care Clin. 1997;13(2):363–376. doi: 10.1016/s0749-0704(05)70315-8. - DOI - PubMed
1. Efu ME, Ojo B, Eke BA, Anefu GO, Ozoagu MA. Characterization of the intensive care unit (ICU) admission in the Benue State University teaching hospital. Med Surg Sci. 2019;6(4):126–128. doi: 10.32457/ijmss.2019.037.Efu. - DOI
1. Kaukonen K, Bailey M, Suzuki S, Pilcher D, Bellomo R. Mortality related to severe sepsis and septic shock among critically ill patients in Australia and New Zealand, 2000–2012. JAMA. 2014;311(13):1308–1316. doi: 10.1001/jama.2014.2637. - DOI - PubMed
1. Needham DM, Davidson J, Cohen H, et al. Improving long-term outcomes after discharge from intensive care unit. Crit Care Med. 2012;40(2):502–509. doi: 10.1097/CCM.0b013e318232da75. - DOI - PubMed
1. Neufeld KJ, Leoutsakos JS, Yan H, et al. Fatigue symptoms during the first year following ARDS. Chest. 2020;158(3):999–1007. doi: 10.1016/j.chest.2020.03.059. - DOI - PMC - PubMed

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[1] Calvin JE, Habet K, Parrillo JE. Critical care in the United States who are we and how did we get here? Crit Care Clin. 1997;13(2):363–376. doi: 10.1016/s0749-0704(05)70315-8. - DOI - PubMed

[2] Calvin JE, Habet K, Parrillo JE. Critical care in the United States who are we and how did we get here? Crit Care Clin. 1997;13(2):363–376. doi: 10.1016/s0749-0704(05)70315-8. - DOI - PubMed

[3] Efu ME, Ojo B, Eke BA, Anefu GO, Ozoagu MA. Characterization of the intensive care unit (ICU) admission in the Benue State University teaching hospital. Med Surg Sci. 2019;6(4):126–128. doi: 10.32457/ijmss.2019.037.Efu. - DOI

[4] Efu ME, Ojo B, Eke BA, Anefu GO, Ozoagu MA. Characterization of the intensive care unit (ICU) admission in the Benue State University teaching hospital. Med Surg Sci. 2019;6(4):126–128. doi: 10.32457/ijmss.2019.037.Efu. - DOI

[5] Kaukonen K, Bailey M, Suzuki S, Pilcher D, Bellomo R. Mortality related to severe sepsis and septic shock among critically ill patients in Australia and New Zealand, 2000–2012. JAMA. 2014;311(13):1308–1316. doi: 10.1001/jama.2014.2637. - DOI - PubMed

[6] Kaukonen K, Bailey M, Suzuki S, Pilcher D, Bellomo R. Mortality related to severe sepsis and septic shock among critically ill patients in Australia and New Zealand, 2000–2012. JAMA. 2014;311(13):1308–1316. doi: 10.1001/jama.2014.2637. - DOI - PubMed

[7] Needham DM, Davidson J, Cohen H, et al. Improving long-term outcomes after discharge from intensive care unit. Crit Care Med. 2012;40(2):502–509. doi: 10.1097/CCM.0b013e318232da75. - DOI - PubMed

[8] Needham DM, Davidson J, Cohen H, et al. Improving long-term outcomes after discharge from intensive care unit. Crit Care Med. 2012;40(2):502–509. doi: 10.1097/CCM.0b013e318232da75. - DOI - PubMed

[9] Neufeld KJ, Leoutsakos JS, Yan H, et al. Fatigue symptoms during the first year following ARDS. Chest. 2020;158(3):999–1007. doi: 10.1016/j.chest.2020.03.059. - DOI - PMC - PubMed

[10] Neufeld KJ, Leoutsakos JS, Yan H, et al. Fatigue symptoms during the first year following ARDS. Chest. 2020;158(3):999–1007. doi: 10.1016/j.chest.2020.03.059. - DOI - PMC - PubMed

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Post-intensive care syndrome (PICS): recent updates

Affiliations

Post-intensive care syndrome (PICS): recent updates

Authors

Affiliations

Abstract

Conflict of interest statement

Figures

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References

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Abstract

Conflict of interest statement

Figures

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References

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