Steps on the Path to Clinical Translation: A workshop by the British and Irish Chapter of the ISMRM

Penny L Hubbard Cristinacce¹, Julia E Markus², Shonit Punwani², Rebecca Mills³, Maria Yanez Lopez⁴, Matthew Grech-Sollars^{5

6}, Fabrizio Fasano⁷, John C Waterton^{8

9}, Michael J Thrippleton¹⁰, Matt G Hall¹¹, James P B O'Connor^{1

12}, Susan T Francis¹³, Ben Statton¹⁴, Kevin Murphy¹⁵, Po-Wah So¹⁶, Harpreet Hyare^{6

17}

Affiliations

¹ Quantitative Biomedical Imaging Laboratory, Division of Cancer Sciences, School of Health Sciences, Faculty of Biology Medicine & Health, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, UK.
² Centre for Medical Imaging, Division of Medicine, University College London, London, UK.
³ University of Oxford, Centre for Clinical Magnetic Resonance Research, The John Radcliffe Hospital, Oxford, UK.
⁴ MR Physics Group, Department of Medical Physics and Clinical Engineering, Swansea Bay University Health Board, Singleton Hospital, Swansea, UK.
⁵ Department of Computer Science, University College London, London, UK.
⁶ Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK.
⁷ Siemens Healthcare Ltd, Camberly, UK.
⁸ Centre for Imaging Sciences, Division of Informatics Imaging & Data Sciences, School of Health Sciences, Faculty of Biology Medicine & Health, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, UK.
⁹ Bioxydyn Limited, Rutherford House, Manchester Science Park, Manchester, UK.
¹⁰ Edinburgh Imaging/Centre for Clinical Brain Sciences, University of Edinburgh, The Chancellor's Building, Edinburgh, UK.
¹¹ National Physical Laboratory, Teddington, UK.
¹² Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, UK.
¹³ Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK.
¹⁴ MRC London Institute of Medical Sciences, Du Cane Road, Imperial College London, London, UK.
¹⁵ Cardiff University Brain Research Imaging Centre, School of Physics and Astronomy, Cardiff, UK.
¹⁶ Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
¹⁷ Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London, UK.

PMID: 37222226
DOI: 10.1002/mrm.29704

Review

Steps on the Path to Clinical Translation: A workshop by the British and Irish Chapter of the ISMRM

Penny L Hubbard Cristinacce et al. Magn Reson Med. 2023 Sep.

. 2023 Sep;90(3):1130-1136.

doi: 10.1002/mrm.29704. Epub 2023 May 24.

Authors

Affiliations

¹ Quantitative Biomedical Imaging Laboratory, Division of Cancer Sciences, School of Health Sciences, Faculty of Biology Medicine & Health, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, UK.
² Centre for Medical Imaging, Division of Medicine, University College London, London, UK.
³ University of Oxford, Centre for Clinical Magnetic Resonance Research, The John Radcliffe Hospital, Oxford, UK.
⁴ MR Physics Group, Department of Medical Physics and Clinical Engineering, Swansea Bay University Health Board, Singleton Hospital, Swansea, UK.
⁵ Department of Computer Science, University College London, London, UK.
⁶ Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK.
⁷ Siemens Healthcare Ltd, Camberly, UK.
⁸ Centre for Imaging Sciences, Division of Informatics Imaging & Data Sciences, School of Health Sciences, Faculty of Biology Medicine & Health, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, UK.
⁹ Bioxydyn Limited, Rutherford House, Manchester Science Park, Manchester, UK.
¹⁰ Edinburgh Imaging/Centre for Clinical Brain Sciences, University of Edinburgh, The Chancellor's Building, Edinburgh, UK.
¹¹ National Physical Laboratory, Teddington, UK.
¹² Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, UK.
¹³ Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK.
¹⁴ MRC London Institute of Medical Sciences, Du Cane Road, Imperial College London, London, UK.
¹⁵ Cardiff University Brain Research Imaging Centre, School of Physics and Astronomy, Cardiff, UK.
¹⁶ Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
¹⁷ Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London, UK.

PMID: 37222226
DOI: 10.1002/mrm.29704

Abstract

The British and Irish Chapter of the International Society for Magnetic Resonance in Medicine (BIC-ISMRM) held a workshop entitled "Steps on the path to clinical translation" in Cardiff, UK, on 7th September 2022. The aim of the workshop was to promote discussion within the MR community about the problems and potential solutions for translating quantitative MR (qMR) imaging and spectroscopic biomarkers into clinical application and drug studies. Invited speakers presented the perspectives of radiologists, radiographers, clinical physicists, vendors, imaging Contract/Clinical Research Organizations (CROs), open science networks, metrologists, imaging networks, and those developing consensus methods. A round-table discussion was held in which workshop participants discussed a range of questions pertinent to clinical translation of qMR imaging and spectroscopic biomarkers. Each group summarized their findings via three main conclusions and three further questions. These questions were used as the basis of an online survey of the broader UK MR community.

Keywords: Imaging biomarkers; clinical translation; consensus; quantitative MRI; survey.

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References

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Steps on the Path to Clinical Translation: A workshop by the British and Irish Chapter of the ISMRM

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Steps on the Path to Clinical Translation: A workshop by the British and Irish Chapter of the ISMRM

Authors

Affiliations

Abstract

References

REFERENCES

Publication types

MeSH terms

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Grants and funding

LinkOut - more resources

Full Text Sources

Medical