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Review
. 2023 Jun;127(8):1264-1270.
doi: 10.1002/jso.27317.

Management of lateral pelvic lymph nodes in rectal cancer

Affiliations
Review

Management of lateral pelvic lymph nodes in rectal cancer

Gloria Chang et al. J Surg Oncol. 2023 Jun.

Abstract

Lateral pelvic lymph node (LPLN) involvement occurs in 10%-25% of rectal cancer cases. Total mesorectal excision (TME) with routine LPLN dissection (LPLND) is predominantly applied in Japan whereas TME with neoadjuvant treatment are used in the West. LPLND is a morbid procedure and minimally invasive techniques may help reduce its morbidity. Selective lateral pelvic node dissection with TME following neoadjuvant treatment achieves acceptable disease-free and overall survival.

Keywords: lateral pelvic lymph nodes; pelvic lymphadenopathy; rectal adenocarcinoma; rectal cancer.

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References

REFERENCES

    1. Hojo K, Koyama Y, Moriya Y. Lymphatic spread and its prognostic value in patients with rectal cancer. Am J Surg. 1982;144(3):350-354. doi:10.1016/0002-9610(82)90018-6
    1. Morikawa E, Yasutomi M, Shindou K, et al. Distribution of metastatic lymph nodes in colorectal cancer by the modified clearing method. Dis Colon Rectum. 1994;37(3):219-223. doi:10.1007/bf02048158
    1. Ogura A, Konishi T, Cunningham C, et al. Neoadjuvant (chemo)radiotherapy with total mesorectal excision only is not sufficient to prevent lateral local recurrence in enlarged nodes: results of the multicenter lateral node study of patients with low cT3/4 rectal cancer. J Clin Oncol. 2019;37(1):33-43. doi:10.1200/JCO.18.00032
    1. MacFarlane JK, Ryall RDH, Heald RJ. Mesorectal excision for rectal cancer. Lancet. 1993;341(8843):457-460. doi:10.1016/0140-6736(93)90207-W
    1. Hashiguchi Y, Muro K, Saito Y, et al. Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer. Int J Clin Oncol. 2020;25(1):1-42. doi:10.1007/s10147-019-01485-z

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