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Review
. 2023 Jun;127(8):1247-1251.
doi: 10.1002/jso.27320.

Colorectal cancer in young adults

Bradford J Kim  1 , Mark H Hanna  2
Affiliations
Review

Colorectal cancer in young adults

Bradford J Kim et al. J Surg Oncol. 2023 Jun.

Abstract

The incidence of colorectal cancer in young adults (CRCYAs) is increasing globally, and it is now the third leading cause of cancer death among young adults under 50 years old. The rising incidence is attributed to various emerging risk factors such as genetics, lifestyle factors, and microbiome profiles. Delayed diagnosis and more advanced disease presentation contribute to worse outcomes. A multidisciplinary approach to care is crucial to ensure comprehensive and personalized treatment plans for CRCYA.

Keywords: colon cancer; rectal cancer; young adults.

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References

REFERENCES

    1. Exarchakou A, Donaldson LJ, Girardi F, Coleman MP. Colorectal cancer incidence among young adults in England: trends by anatomical sub-site and deprivation. PLoS One. 2019;14:e0225547.
    1. Chambers AC, Dixon SW, White P, Williams AC, Thomas MG, Messenger DE. Demographic trends in the incidence of young-onset colorectal cancer: a population-based study. Br J Surg. 2020;107:595-605.
    1. Lui RN, Tsoi KKF, Ho JMW, et al. Global increasing incidence of young-onset colorectal cancer across 5 continents: a joinpoint regression analysis of 1,922,167 cases. Cancer Epidemiol Biomarkers Prev. 2019;28:1275-1282.
    1. Screening for colorectal cancer: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2008;149:627-637.
    1. Done JZ, Fang SH. Young-onset colorectal cancer: a review. World J Gastrointest Oncol. 2021;13:856-866.

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