Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Apr 22;15(4):e37982.
doi: 10.7759/cureus.37982. eCollection 2023 Apr.

Trends in Breast Cancer Incidence and Mortality in the United States From 2004-2018: A Surveillance, Epidemiology, and End Results (SEER)-Based Study

Talal Bazzi  1 , Muneer Al-Husseini  1 , Louis Saravolatz  2 , Zyad Kafri  3
Affiliations

Trends in Breast Cancer Incidence and Mortality in the United States From 2004-2018: A Surveillance, Epidemiology, and End Results (SEER)-Based Study

Talal Bazzi et al. Cureus. .

Abstract

The incidence and mortality data for patients with breast cancer in the United States are important to healthcare administrators for planning healthcare measures such as screening mammograms. In this study, we examined breast cancer incidence and incidence-based mortality in the United States from 2004-2018 using the Surveillance, Epidemiology, and End Results (SEER) database. We reviewed 915,417 cases of breast cancer diagnosed between 2004 and 2018. Overall, the data showed an increased incidence rate of breast cancer among all races and a decreased mortality rate among all races. Breast cancer incidence rates increased by 0.3% (95% CI, 0.1, 0.4, p<0.001) per year over the study period. Breast cancer incidence rates increased for all age, race, and stage groups except for stage regional, which showed a statistically significant decrease in the incidence of -0.9% (95% CI, -1.1, -0.7, p<0.001). The highest decrease in mortality was observed among white patients, with an overall statistically significant decrease in rates by -14.3% (95% CI, -18.1, -10.4, p <0.001). The highest decrease in rates was observed between 2016 and 2018: -48.6 (95% CI, -52.6, -44.3, p <0.001). In black/African American patients, the overall incidence-based mortality decreased by -11.6% (95% CI -15.9, -7.1 p <.001), with the highest decrease in rates observed between 2016 and 2018 with a decrease of -51.3% (95% CI -56.6, -45.3, p <0.001). In Hispanic Americans, the overall incidence-based mortality decreased by -12.3% (95% CI -16.9, -7.4, p <.001), which is lower than in white Americans.

Keywords: breast cancer incidence; breast cancer mortality; breast cancer research; breast cancer trends; seer database.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

References

    1. Incidence and mortality and epidemiology of breast cancer in the world. Ghoncheh M, Pournamdar Z, Salehiniya H. Asian Pac J Cancer Prev. 2016;17:43–46. - PubMed
    1. Incidence and mortality of breast cancer and their relationship with the human development index (HDI) in the World in 2012. Ghoncheh M, Mirzaei M, Salehiniya H. Asian Pac J Cancer Prev. 2015;16:8439–8443. - PubMed
    1. Breast-cancer tumor size, overdiagnosis, and mammography screening effectiveness. Welch HG, Prorok PC, O'Malley AJ, Kramer BS. N Engl J Med. 2016;375:1438–1447. - PubMed
    1. Surveillance Research Program. National Cancer Institute: SEER*Stat software version 8.3.4. [ May; 2022 ]. https://seer.cancer.gov/seerstat/ https://seer.cancer.gov/seerstat/
    1. A method for partitioning cancer mortality trends by factors associated with diagnosis: An application to female breat cancer. Chu KC, Miller BA, Feuer EJ, et al. http://10.1016/0895-4356(94)90089-2. J Clin Epidemiol. 1994;47:1451–1461. - PubMed

LinkOut - more resources