Precision diagnosis and staging of TDP-43 proteinopathies: harnessing the power of artificial intelligence
- PMID: 37224516
- PMCID: PMC10316762
- DOI: 10.1093/brain/awad175
Precision diagnosis and staging of TDP-43 proteinopathies: harnessing the power of artificial intelligence
Abstract
This scientific commentary refers to ‘Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies’ by Young et al. (
Conflict of interest statement
S.W.S. serves on the Scientific Advisory Council of the Lewy Body Dementia Association and the Multiple System Atrophy Coalition. S.W.S. receives research support from Cerevel Therapeutics. S.W.S. is an editorial board member of the Journal of Parkinson’s Disease and JAMA Neurology. The views expressed in this article are those of the authors and do not necessarily reflect the views or policies of the Uniformed Services University, the United States Department of Defense, the United States government, or the Henry M. Jackson Foundation for the Advancement of Military Medicine.
Figures
Comment on
-
Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies.Brain. 2023 Jul 3;146(7):2975-2988. doi: 10.1093/brain/awad145. Brain. 2023. PMID: 37150879 Free PMC article.
References
-
- Wilson DM 3rd, Cookson MR, Van Den Bosch L, Zetterberg H, Holtzman DM, Dewachter I. Hallmarks of neurodegenerative diseases. Cell. 2023; 186:693–714. - PubMed
-
- Neumann M, Sampathu DM, Kwong LK, et al. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science. 2006; 314:130–133. - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Medical
