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Editorial
. 2023 Jun;20(6):555-557.
doi: 10.1038/s41423-023-01034-9. Epub 2023 May 24.

Mesenchymal stem/stromal cells (MSCs): origin, immune regulation, and clinical applications

Jun Zhou  1 , Yufang Shi  2
Affiliations
Editorial

Mesenchymal stem/stromal cells (MSCs): origin, immune regulation, and clinical applications

Jun Zhou et al. Cell Mol Immunol. 2023 Jun.
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

None
Dr. Yufang Shi
None
Dr. Jun Zhou
Fig. 1
Fig. 1
The origin, immune regulation, and clinical applications of MSCs. MSCs exist in almost all tissues. These cells play critical roles in not only tissue regeneration but also the pathogenic process by interacting with various immune cells in different activation stages. MSCs can also be robustly expanded in vitro and applied to patients to control inflammatory diseases and promote tissue regeneration
See this image and copyright information in PMC

References

    1. Karin M, Clevers H. Reparative inflammation takes charge of tissue regeneration. Nature. 2016;529:307–15. doi: 10.1038/nature17039. - DOI - PMC - PubMed
    1. Aurora AB, Olson EN. Immune modulation of stem cells and regeneration. Cell Stem Cell. 2014;15:14–25. doi: 10.1016/j.stem.2014.06.009. - DOI - PMC - PubMed
    1. Friedenstein AJ, Chailakhjan RK, Lalykina KS. The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells. Cell Tissue Kinet. 1970;3:393–403. - PubMed
    1. Caplan A. Mesenchymal stem cells. J Orthop Res. 1991;9:641–50. doi: 10.1002/jor.1100090504. - DOI - PubMed
    1. Viswanathan S, Shi Y, Galipeau J, Krampera M, Leblanc K, Martin I, et al. Mesenchymal stem versus stromal cells: International Society for Cell & Gene Therapy (ISCT(R)) Mesenchymal Stromal Cell committee position statement on nomenclature. Cytotherapy. 2019;21:1019–24. doi: 10.1016/j.jcyt.2019.08.002. - DOI - PubMed

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