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Case Reports
. 2023 Jul-Aug;34(5):e505-e507.
doi: 10.1097/SCS.0000000000009378. Epub 2023 May 25.

Diagnosis and Treatment of Rare Adult Embryonal Rhabdomyosarcoma in Maxillary Sinus

Yue Liu  1 , Yan Liu, Lian Ji Wen, Dan Yu
Affiliations
Case Reports

Diagnosis and Treatment of Rare Adult Embryonal Rhabdomyosarcoma in Maxillary Sinus

Yue Liu et al. J Craniofac Surg. 2023 Jul-Aug.

Abstract

Objective: To investigate the clinicopathological features, imaging features, diagnosis, and prognosis of embryonal rhabdomyosarcoma (ERMS) in the maxillary sinus.

Methods: The detailed clinical data of rare patients with embryonal ERMS of maxillary sinus admitted to our hospital were retrospectively analyzed, and the embryonal ERMS was confirmed by pathological examination and immunohistochemistry, and the relevant literature was reviewed.

Results: A 58-year-old man was admitted to the hospital with the chief complaint of "numbness and swelling of the left cheek for 1 and a half months". Blood routine, biochemistry, paranasal sinus computed tomography, and magnetic resonance imaging were performed after admission, and the pathology showed ERMS. At present, it is generally in good condition. Pathological examination showed that the cells were all small and round. Immunohistochemistry showed Desmin (+) and Ki-67 (+70%).

Conclusion: The early symptoms of ERMS of the maxillary sinus are atypical and diverse, with a high degree of malignancy, rapid progression, strong invasiveness, and poor prognosis. Early diagnosis and treatment should be based on clinical characteristics, imaging examination, and immunohistochemical results.

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Conflict of interest statement

The authors report no conflicts of interest.

References

    1. Bisogno G, De Salvo GL, Bergeron C, et al. Vinorelbine and continuous low-dose cyclophosphamide as maintenance chemotherapy in patients with high-risk rhabdomyosarcoma (RMS 2005): a multicentre, open-label, randomised, phase 3 trial. Lancet Oncol 2019;20:1566–1575
    1. Xie RH, Liu WF, Yang HQ, et al. Embryonal rhabdomyosarcoma of the nasal vestibule: case report. Southwest Military Doctor 2014;16:387
    1. Sbaraglia M, Bellan E, Dei Tos AP. The 2020 WHO classification of soft tissue tumours: news and perspectives. Pathologica 2021;113:70–84
    1. Stepan K, Konuthula N, Khan M, et al. Outcomes in adult sinonasal rhabdomyosarcoma. Otolaryngol Head Neck Surg 2017;157:135–141
    1. Carter CS, East EG, McHugh JB, et al. Biphenotypic sinonasals sarcoma:a review and update. Arch Pathol Lab Med 2018;142:1196–1201

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